YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAP27G11.04c
Organism:	Schizosaccharomyces pombe
Length:	315 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAP27G11.04c.

Description	E-value	Query Range	Subject Range
gi\|22204218 - gi\|22204218\|emb\|CAD43470.1\| novel protein [Danio rerio]	230.0	[0..21]	[305..18]
TAD3 - Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad2p that converts adenos... TAD3_YEAST - tRNA-specific adenosine deaminase subunit TAD3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28...	228.0	[0..19]	[313..18]
ADAT3 - adenosine deaminase, tRNA-specific 3, TAD3 homolog (S. cerevisiae)	226.0	[0..13]	[305..15]
gi\|109122760, gi... - gi\|109122760\|ref\|XP_001096552.1\| PREDICTED: similar to CG10927-PA isoform 2 [Macaca mulatta], gi\|109...	225.0	[0..13]	[306..15]
ADAT3_MOUSE - Probable inactive tRNA-specific adenosine deaminase-like protein 3 OS=Mus musculus GN=Adat3 PE=1 SV=...	224.0	[0..11]	[305..13]
gi\|76622836 - gi\|76622836\|ref\|XP_872435.1\| PREDICTED: similar to CG10927-PA [Bos taurus]	219.0	[0..13]	[304..8]
ADAT3_RAT - Probable inactive tRNA-specific adenosine deaminase-like protein 3 OS=Rattus norvegicus GN=Adat3 PE=...	214.0	[0..11]	[305..13]
gi\|57102218 - gi\|57102218\|ref\|XP_542193.1\| PREDICTED: similar to CG10927-PA [Canis familiaris]	209.0	[0..6]	[304..8]

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Predicted Domain #1

Region A:
Residues: [1-151]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKTNISKNS PKEATVPELD WPFKLIKSHL ETRKLETENV WIACFEPKYA SKVTQYVKQI  60
   61 RSKQKESLLH CNRLRRIQDE NGSLELQIII CPEKSMTANE IGKDFEDLGI VSKMIFLYAV 120
  121 PAFPPLTDEQ FHEWNSVWPV SYRKHVQRQD V

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [152-315]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTVHELKRIE SILEDLINAA GASHKHGEIG CAAAIYDPTT DTVLAVSVDE RSKLKNPINH  60
   61 CVMNAINLVA KRELSRRQNR TDGSKDRYLC KDLTVVMTHE PCVMCSMGLL HSRIRRLIYC 120
  121 KKQPLTGGIE SLYGIHWRAE LNHRYLAYSG WNKPVPSIKE NIHV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.221849
Match:	1z3aA
Description:	Crystal structure of tRNA adenosine deaminase TadA from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.70756445127105	bayes_pls_golite062009
binding	1.64474382695496	bayes_pls_golite062009
methyltransferase activity	1.24697538679504	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.16679252289538	bayes_pls_golite062009
transferase activity	0.771056210634777	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	0.113989053833271	bayes_pls_golite062009
protein binding	0.072557222523031	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: