YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC215.11c
Organism:	Schizosaccharomyces pombe
Length:	306 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC215.11c.

Description	E-value	Query Range	Subject Range
gi\|67861532, gi\|... - gi\|67931231\|ref\|ZP_00524395.1\| Aldo/keto reductase [Solibacter usitatus Ellin6076], gi\|67861532\|gb\|E...	283.0	[0..13]	[295..1]
gi\|53765455, gi\|... - gi\|75906333\|ref\|YP_320629.1\| aldo/keto reductase [Anabaena variabilis ATCC 29413], gi\|75700058\|gb\|AB...	282.0	[0..13]	[295..2]
gi\|50119681, gi\|... - gi\|50119681\|ref\|YP_048848.1\| putative aldo/keto reductase [Pectobacterium atrosepticum SCRI1043], gi...	278.0	[0..13]	[293..1]
gi\|46399818, gi\|... - gi\|46446177\|ref\|YP_007542.1\| MocA family oxidoreductase [Candidatus Protochlamydia amoebophila UWE25...	278.0	[0..13]	[300..1]
gi\|108467371, gi... - gi\|108763491\|ref\|YP_632183.1\| aldo/keto reductase family oxidoreductase [Myxococcus xanthus DK 1622]...	277.0	[0..13]	[296..1]
gi\|76166661, gi\|... - gi\|76258577\|ref\|ZP_00766232.1\| Aldo/keto reductase [Chloroflexus aurantiacus J-10-fl], gi\|76166661\|g... gi\|222524644, gi... - gi\|222524644\|ref\|YP_002569115.1\| aldo/keto reductase [Chloroflexus sp. Y-400-fl], gi\|222448523\|gb\|AC...	277.0	[0..13]	[296..1]
gi\|33596263 - gi\|33596263\|ref\|NP_883906.1\| putative oxidoreductase [Bordetella parapertussis 12822] gi\|33573266 - gi\|33573266\|emb\|CAE36928.1\| putative oxidoreductase [Bordetella parapertussis]	276.0	[0..13]	[298..1]
gi\|237797143, gi... - gi\|237797143\|ref\|YP_002887433.1\| putative oxidoreductase [Pseudomonas fluorescens], gi\|229424280\|gb\|... gi\|38638513, gi\|... - gi\|38638513\|ref\|NP_943099.1\| oxido-reductase/dehydratase [Pseudomonas sp. ND6], gi\|34335301\|gb\|AAP44... gi\|114050463 - gi\|114050463\|dbj\|BAF30949.1\| putative oxidoreductase [uncultured bacterium] gi\|28976073, gi\|... - gi\|32469911\|ref\|NP_863085.1\| putative oxidoreductase [Pseudomonas putida], gi\|28976073\|gb\|AAO64287.1...	276.0	[0..13]	[303..1]
gi\|29604544, gi\|... - gi\|29827445\|ref\|NP_822079.1\| oxidoreductase [Streptomyces avermitilis MA-4680], gi\|29604544\|dbj\|BAC6...	276.0	[0..13]	[304..1]
gi\|33602077, gi\|... - gi\|33602077\|ref\|NP_889637.1\| putative oxidoreductase [Bordetella bronchiseptica RB50], gi\|33576515\|e...	276.0	[0..13]	[298..1]

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Predicted Domain #1

Region A:
Residues: [1-306]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKTAASSAV DASQAGTVKV GDMVVNRMGF GAMRVTGDGI WDEPKDKEAC IATLKRLPEL  60
   61 NINFIDTADS YGPEVSENLL REALYPYKGL IIATKGGLVR TGPNEWHPCG APKFLRQEVL 120
  121 MSMRRLGVKQ IDLWQLHRID PKVPRKDQFS EIAAMKKEGL IRHVGLSEVT VDDIKEAEQY 180
  181 FPVVSVQNLF NLVNRKNEKV LEYCEQKGIA FIPWYPLASG ALAKPGTILD AVSKDLDRST 240
  241 SQIALSWVLQ RSPVMLPIPG TSKVDHLEEN VKAAGIQLSS EVFAKLDEEG KSEDAKRQEE 300
  301 EKKKSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.0
Match:	1pyfA
Description:	Structure of NADPH-dependent family 11 aldo-keto reductase AKR11A(apo)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
pyridoxine 4-dehydrogenase activity	3.25535446462297	bayes_pls_golite062009
aldo-keto reductase activity	2.57303336304449	bayes_pls_golite062009
aryl-alcohol dehydrogenase activity	2.5168190536972	bayes_pls_golite062009
catalytic activity	1.68179794468736	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.48881830724998	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47641884930911	bayes_pls_golite062009
oxidoreductase activity	1.17915737521094	bayes_pls_golite062009
aldehyde reductase activity	1.16639404121425	bayes_pls_golite062009
binding	0.750554688914866	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: