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View Structure Prediction Details

Protein: apl5
Organism: Schizosaccharomyces pombe
Length: 834 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for apl5.

Description E-value Query
Range
Subject
Range
gi|62087188 - gi|62087188|dbj|BAD92041.1| Adapter-related protein complex 3 delta 1 subunit variant [Homo sapiens]
425.0 [0..2] [729..82]
gi|114674483 - gi|114674483|ref|XP_001149847.1| PREDICTED: adaptor-related protein complex 3, delta 1 subunit isofo...
415.0 [0..2] [729..13]
gi|73987264 - gi|73987264|ref|XP_854547.1| PREDICTED: similar to Adapter-related protein complex 3 delta 1 subunit...
414.0 [0..2] [729..13]
gi|27370771 - gi|27370771|gb|AAH37477.1| Ap3d1 protein [Mus musculus]
411.0 [0..2] [729..13]

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Predicted Domain #1
Region A:
Residues: [1-615]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFERTLIDL IKGIRSHAND EEAFIATCLL ECRKEATSQD ADLKSEAILK LAYLEMLGVD  60
   61 ISWASFQIVE VMSSSKILQK QKGYLAAVQS FKPDTDVLML TTNLLKKDLM SSKVPEITLA 120
  121 IDGLSHFSTL GLARDLYRDV LILLNHSVPY VRKRTILLLY RLCLQYPEAI SACIPKLRER 180
  181 LDDPDTSVVN AAVSVICELA RRAPKNYLEF APDLFHLLTT SSNNWMLIKL IKLFASLTPY 240
  241 EPRLVKKLIP SLTDIIENTH AMSLLYECIN TIVSGNMLVG HSQCDKLASL CASKLRGFFE 300
  301 DTDQNLKYIA LLCLRKLANT HPSLVSAQLD IILKCLVDTD TSIRLRALDL VNEIVNKENI 360
  361 RTIVKTLMLQ LIVSSDESAV EDIRNSTATR IIEMTSKSTY MNIADFEWLL TVYVDLANIP 420
  421 GIDTGTLLNN QIIDLCVRVK ALRPFSVDIF SQAILDPSYV STTDCSVSEK RTDILPAIIW 480
  481 CLGEYAEFIE EYLDILDALT RPSFKKCSNL AHRLLLQAIT KIFCQWCLEE EPTWGVEKFG 540
  541 LVKLWVEKIV SFIEQFLNFQ DMEIQRRASE FYILFNQVSD IVNTSDTMEV LELQKKPPYI 600
  601 VQNTMYKLFF GEPLN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.39794
Match: 1w63A
Description: AP1 clathrin adaptor core
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [616-692]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVAVKAQRKV MPDENLDLNC PINGVIEVPK ELLENIIQSD DSLINFDTEV PSSGIDTFSK  60
   61 KQFNSLESVP VQRDLSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.39794
Match: 1pzdA
Description: Structural Identification of a conserved appendage domain in the carboxyl-terminus of the COPI gamma-subunit.
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [693-834]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PFYLSSNQHT TTTNSEPENL NVETSMSDEA FNADKVTKGL LMLLIILFLL IILVTKNKRR  60
   61 RKIFTSPSLQ AMVVAQDEVP EGISLADIEN KENPSNSNVY SLISLDPPLS TNQGSMGDIV 120
  121 LETKSPIRVE KKKSKKKKKK KV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle