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View Structure Prediction Details

Protein: SPBC543.02c
Organism: Schizosaccharomyces pombe
Length: 476 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC543.02c.

Description E-value Query
Range
Subject
Range
gi|33640682, gi|... - gi|33862569|ref|NP_894129.1| TPR repeat-containing protein [Prochlorococcus marinus str. MIT 9313], ...
201.0 [0..3] [453..483]
gi|113475191, gi... - gi|113475191|ref|YP_721252.1| glycosyl transferase family protein [Trichodesmium erythraeum IMS101],...
200.0 [0..4] [447..27]
gi|32403286, gi|... - gi|32403286|ref|XP_322256.1| hypothetical protein [Neurospora crassa], gi|28917756|gb|EAA27447.1| co...
gi|85081220 - gi|85081220|ref|XP_956683.1| hypothetical protein NCU00170 [Neurospora crassa OR74A]
199.0 [0..21] [416..290]
gi|73670079, gi|... - gi|73670079|ref|YP_306094.1| TPR repeat-containing protein [Methanosarcina barkeri str. Fusaro], gi|...
195.0 [0..1] [455..199]
gi|118381868 - gi|118381868|ref|XP_001024094.1| TPR Domain containing protein [Tetrahymena thermophila]
gi|118381868, gi... - gi|89305861|gb|EAS03849.1| TPR Domain containing protein [Tetrahymena thermophila SB210], gi|1183818...
189.0 [0..5] [447..19]
gi|90303208, gi|... - gi|90303208|gb|EAS32839.1| hypothetical protein CIMG_03863 [Coccidioides immitis RS], gi|119187631|r...
186.0 [0..22] [455..241]

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Predicted Domain #1
Region A:
Residues: [1-476]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEVETTHMN AGTESQQEPA ELAEKQKAIG NAFYKEKKYA EAIKAYTEAI DLGSDSALAI  60
   61 YYSNRAATYM QIGEFELALC DAKQSDRIKP DVPKTQSRIR QAYEGLSILN EAEVYLKNKQ 120
  121 AGLALNALDR LQRRIDSTTQ PPMSWMYLKA QVYIFQNDMD RAQKIAHDVL RLNPKNVEAL 180
  181 VLRGKVMYYS GENAKAITHF QEALKLDPDC TTAKTLFKQV RKLENTKNQG NDLFRQGNYQ 240
  241 DAYEKYSEAL QIDPDNKETV AKLYMNRATV LLRLKRPEEA LSDSDNALAI DSSYLKGLKV 300
  301 RAKAHEALEK WEEAVRDVQS AIELDASDAN LRQELRRLQL ELKKSKRKDH YKILGVSKEA 360
  361 TDIEIKKAYR KLALVYHPDK NAGNLEAEAR FKEVGEAYTI LSDPESRRRF DSGVDLEPGM 420
  421 EGGAGMDPFD ILRAYQAGGS FPGGGFPGGG FPGGSYNSQG FGMGGGFPGF TSFQFS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.0
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.48701537593139 bayes_pls_golite062009
heat shock protein binding 1.35268080101836 bayes_pls_golite062009
unfolded protein binding 1.03065657981002 bayes_pls_golite062009
protein binding 0.931467806305272 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle