YRC Public Data Repository - Protein Structure Prediction

Protein:	cys2
Organism:	Schizosaccharomyces pombe
Length:	504 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cys2.

Description	E-value	Query Range	Subject Range
gi\|90301654, gi\|... - gi\|90301654\|gb\|EAS31285.1\| hypothetical protein CIMG_06764 [Coccidioides immitis RS], gi\|119183740\|r...	311.0	[0..4]	[502..2479]
gi\|49126040, gi\|... - gi\|67903156\|ref\|XP_681834.1\| hypothetical protein AN8565.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	310.0	[0..3]	[502..40]
gi\|149211203, gi... - gi\|86197017\|gb\|EAQ71655.1\| hypothetical protein MGCH7_ch7g1062 [Magnaporthe grisea 70-15], gi\|399693...	301.0	[0..4]	[502..641]
gi\|2605934 - gi\|2605934\|gb\|AAB84208.1\| putative serine O-acetyltransferase [Emericella nidulans]	296.0	[0..3]	[486..40]
gi\|85111755 - gi\|85111755\|ref\|XP_964088.1\| hypothetical protein NCU00536 [Neurospora crassa OR74A] gi\|32408469, gi\|... - gi\|32408469\|ref\|XP_324716.1\| hypothetical protein [Neurospora crassa], gi\|28925853\|gb\|EAA34852.1\| hy...	296.0	[0..9]	[502..53]
gi\|159126487 - gi\|159126487\|gb\|EDP51603.1\| homoserine O-acetyltransferase [Aspergillus fumigatus A1163] gi\|70998092, gi\|... - gi\|70998092\|ref\|XP_753777.1\| homoserine O-acetyltransferase [Aspergillus fumigatus Af293], gi\|668514...	292.0	[0..7]	[501..57]
gi\|42546065, gi\|... - gi\|46105116\|ref\|XP_380362.1\| hypothetical protein FG00186.1 [Gibberella zeae PH-1], gi\|42546065\|gb\|E...	292.0	[0..8]	[501..41]
gi\|114191843, gi... - gi\|115398742\|ref\|XP_001214960.1\| hypothetical protein ATEG_05782 [Aspergillus terreus NIH2624], gi\|1...	290.0	[0..6]	[502..57]
gi\|83772692 - gi\|83772692\|dbj\|BAE62820.1\| unnamed protein product [Aspergillus oryzae] gi\|169778977 - gi\|169778977\|ref\|XP_001823953.1\| hypothetical protein [Aspergillus oryzae RIB40]	285.0	[0..7]	[501..41]
gi\|45190509, gi\|... - gi\|45190509\|ref\|NP_984763.1\| AEL098Wp [Ashbya gossypii ATCC 10895], gi\|44983451\|gb\|AAS52587.1\| AEL09... gi\|44983451 - gi\|44983451\|gb\|AAS52587.1\| AEL098Wp [Ashbya gossypii ATCC 10895]	283.0	[0..17]	[502..15]

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Predicted Domain #1

Region A:
Residues: [1-80]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRASSKRLQ LSWQVFRRFQ SSNPQLSFPC VDQAQERSRQ FEQSLQKQQA CPNSVDPSAS  60
   61 ITSPSLSSGP EPVYGKIVSG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [81-441]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FKKFYHNKPF LCDHGGILPK FEIAYETWGT LNKDHSNAIL LHTGLSASSH AHSHPENTAP  60
   61 GWWEQFIGPG KDVDTNKFFV ICTNVLGSCY GSTGPSSVDP GDGKHYATRF PIITVNDMIR 120
  121 AQLLLLDHLK IEKLYASVGS SLGGMQSLTL GALAPHRVGR IASISGGARS HPYSIALRFT 180
  181 QRQILMNDPY WNRGFYYDGV PPHTGMKLAR EVATISYRSG PEWEQRFGNR RADPSVSPAF 240
  241 CPDFLIETYL DHAGEKFCLQ YDPNSLLYIS KAMDMHDMSA SHQRSLSENR KKNQHKLDKY 300
  301 LSADVSAEEI IKLNEDTSVL PDVPYQEIAN EDRAPEPDPE TNLIAGLAPL KDTPVMVMGV 360
  361 E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.0
Match:	2b61A
Description:	Crystal Structure of Homoserine Transacetylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.39629727416851	bayes_pls_golite062009
O-acyltransferase activity	0.588283022438791	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.264183693934251	bayes_pls_golite062009
O-acetyltransferase activity	0.26391491736036	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [442-504]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDNLMPVECQ RETARCLEKA GNKQVVYHEL DANESFYGHD TFLIYRKDLD LVGGKLKKFL  60
   61 ELS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.7
Match:	2b61A
Description:	Crystal Structure of Homoserine Transacetylase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: