YRC Public Data Repository - Protein Structure Prediction

Protein:	aut12
Organism:	Schizosaccharomyces pombe
Length:	513 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for aut12.

Description	E-value	Query Range	Subject Range
gi\|114586954 - gi\|114586954\|ref\|XP_001166744.1\| PREDICTED: MON1 homolog A isoform 4 [Pan troglodytes]	687.0	[0..1]	[513..137]
gi\|13874543 - gi\|13874543\|dbj\|BAB46888.1\| hypothetical protein [Macaca fascicularis]	681.0	[0..1]	[513..62]
gi\|55620341, gi\|... - gi\|55620341\|ref\|XP_516471.1\| PREDICTED: MON1 homolog A isoform 5 [Pan troglodytes], gi\|114586959\|ref... MON1A - MON1 homolog A (yeast)	676.0	[0..1]	[513..40]
gi\|238011010 - gi\|238011010\|gb\|ACR36540.1\| unknown [Zea mays] gi\|34865922, gi\|... - gi\|34865922\|ref\|XP_236627.2\| PREDICTED: similar to MON1 homolog A [Rattus norvegicus], gi\|171847082\|...	668.0	[0..1]	[513..40]
MON1A_MOUSE - Vacuolar fusion protein MON1 homolog A OS=Mus musculus GN=Mon1a PE=1 SV=3	666.0	[0..7]	[513..53]
gi\|73985759 - gi\|73985759\|ref\|XP_850897.1\| PREDICTED: similar to MON1 homolog A [Canis familiaris]	662.0	[0..1]	[513..63]
MON1A_BOVIN - Vacuolar fusion protein MON1 homolog A OS=Bos taurus GN=MON1A PE=2 SV=1	657.0	[0..1]	[513..40]

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Predicted Domain #1

Region A:
Residues: [1-99]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPTSEHSSI KEEVENDNVH RSHESECGSL LLNPGNVLMA APSVSEDDQE VSRSTPELRS  60
   61 HVENVEQLLS DILHDNSSPL NVSTSVSSSS NNTAVDEII

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [100-329]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLLSLISFDL AKQKRTYLIF SSSGKPVFSN IVDDSIEPST VGALQAIISS FEVSKEELTS  60
   61 FSTFSNVIVV LSKNPLYLVG VSPSTTLSAA YLLSELNLLY CQILTGVTAK AMQLTLNSRP 120
  121 NFDLRRLIGS NEQFLKELCD QLNDYELVPT LNAISPLPLR SSFRDQLSQL LLRETPKSLL 180
  181 FTFIAIRGRL VCMVKAKKLL LHANDLYLLF LSLFRTQSFN DSMEHWVPVC

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.993
Match:	1w63Q
Description:	AP1 clathrin adaptor core
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [330-513]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPTLNPDAYI YIYSYFLCKD TVLIMGSSES GVFFEMQSVK CKVAQEIQDH GWLKKLIYCE  60
   61 EMDRTTPRNP GSPCISHYLF YSKKYSQFYT PGYSFSTPNF NTRTLYAIYA SLHDQAFHKK 120
  121 NSFSINMTVH ESLLLFTWST ASFDFHCIAN ATTSSQLLIA NVNKILRWIR REENRLFIQT 180
  181 NLSF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits