YRC Public Data Repository - Protein Structure Prediction

Protein:	tps1
Organism:	Schizosaccharomyces pombe
Length:	513 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tps1.

Description	E-value	Query Range	Subject Range
gi\|11281420, gi\|... - gi\|535003\|emb\|CAA82861.1\| trehalose-6-phosphate synthase [Schizosaccharomyces pombe], gi\|11281420\|pi...	406.0	[0..1]	[477..1]
gi\|109137809 - gi\|109137809\|gb\|ABG25558.1\| trehalose-6-phosphate synthase [Botryotinia fuckeliana]	397.0	[0..9]	[490..2]
gi\|42551067, gi\|... - gi\|46123347\|ref\|XP_386227.1\| hypothetical protein FG06051.1 [Gibberella zeae PH-1], gi\|42551067\|gb\|E...	397.0	[0..19]	[487..83]
gi\|83767458 - gi\|83767458\|dbj\|BAE57597.1\| unnamed protein product [Aspergillus oryzae] gi\|169770259 - gi\|169770259\|ref\|XP_001819599.1\| hypothetical protein [Aspergillus oryzae RIB40]	396.0	[0..9]	[501..2]
gi\|32419843, gi\|... - gi\|32419843\|ref\|XP_330365.1\| hypothetical protein [Neurospora crassa], gi\|28920347\|gb\|EAA29718.1\| al... gi\|85091545 - gi\|85091545\|ref\|XP_958954.1\| alpha,alpha-trehalose-phosphate synthase [Neurospora crassa OR74A]	396.0	[0..9]	[490..1]
gi\|3540 - gi\|3540\|emb\|CAA43580.1\| cif1 [Saccharomyces cerevisiae]	396.0	[0..14]	[481..11]
gi\|44982233 - gi\|44982233\|gb\|AAS51542.1\| ADL378Wp [Ashbya gossypii ATCC 10895] gi\|44982233, gi\|... - gi\|45187495\|ref\|NP_983718.1\| ADL378Wp [Ashbya gossypii ATCC 10895], gi\|44982233\|gb\|AAS51542.1\| ADL37...	395.0	[0..14]	[488..19]
gi\|66848806, gi\|... - gi\|70992649\|ref\|XP_751173.1\| trehalose-phosphate synthase/phosphatase complex subunit Tps1, putative... gi\|119472879, gi... - gi\|119472879\|ref\|XP_001258435.1\| alpha,alpha-trehalose-phosphate synthase subunit TPS1, putative [Ne...	393.0	[0..9]	[500..2]
gi\|49527447, gi\|... - gi\|50291407\|ref\|XP_448136.1\| unnamed protein product [Candida glabrata], gi\|49527447\|emb\|CAG61087.1\|... gi\|49527447 - gi\|49527447\|emb\|CAG61087.1\| unnamed protein product [Candida glabrata]	393.0	[0..18]	[482..10]

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Predicted Domain #1

Region A:
Residues: [1-513]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDAHDTIKS LTGDASNSRR LIVVSNRLPI TIKRKDNGTY DFSMSSGGLV SALSGLKKLM  60
   61 TFQWLGWCGQ EIPEDEKPMI IQRLQDECSA IPVFLDDETA DRHYNGFSNS ILWPLFHYHP 120
  121 GEINFDEENW EAYRAANYAF AEAIVKNLQD GDLIWVQDYH LMVLPQMLRE LIGDKFKDIK 180
  181 IGFFLHTPFP SSEIYRVLPV RNEILEGVLN CDLVGFHTYD YARHFLSACS RILNLSTLPN 240
  241 GVEYNGQMVS VGTFPIGIDP EKFSDALKSD VVKDRIASIE RRLQGVKVIV GVDRLDYIKG 300
  301 VPQKFHAFEV FLEQYPEWVG KVVLVQVAVP SRQDVEEYQN LRAVVNELVG RINGRFGTVE 360
  361 YTPIHFLHKS VRFEELVALY NVSDVCLITS TRDGMNLVSY EYICTQQERH GALILSEFAG 420
  421 AAQSLNGSIV INPWNTEELA NSIHDALTMP EKQREANENK LFRYVNKYTS QFWGQSFVGE 480
  481 LQRIQHYSHP HPRRTNPILR TKSAQVLSMN SSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.69897
Match:	1uqtA
Description:	Trehalose-6-phosphate from E. coli bound with UDP-2-fluoro glucose.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	11.2045941324603	bayes_pls_golite062009
glucosyltransferase activity	8.25064561355471	bayes_pls_golite062009
UDP-glucosyltransferase activity	8.0463972704113	bayes_pls_golite062009
trehalose-phosphatase activity	7.58500038184065	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	3.70184884300914	bayes_pls_golite062009
catalytic activity	2.65148466065976	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.62403914335522	bayes_pls_golite062009
transferase activity	2.18054407163329	bayes_pls_golite062009
UDP-glycosyltransferase activity	2.13085705769565	bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity	1.55280519670033	bayes_pls_golite062009
carbohydrate phosphatase activity	0.78952375993773	bayes_pls_golite062009
glycogen phosphorylase activity	0.607220464589157	bayes_pls_golite062009
binding	0.345236672370351	bayes_pls_golite062009
phosphorylase activity	0.296436712681472	bayes_pls_golite062009
mannosyltransferase activity	0.253888301381021	bayes_pls_golite062009
protein binding	0.198267161626932	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: