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View Structure Prediction Details

Protein: SPBC8D2.06
Organism: Schizosaccharomyces pombe
Length: 1064 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC8D2.06.

Description E-value Query
Range
Subject
Range
gi|109505545, gi... - gi|208022685|ref|NP_001094042.1| isoleucine tRNA synthetase [Rattus norvegicus], gi|149045018|gb|EDL...
910.0 [0..4] [1063..10]
SYIC_MOUSE - Isoleucine--tRNA ligase, cytoplasmic OS=Mus musculus GN=Iars PE=1 SV=2
906.0 [0..4] [1063..10]
gi|62088048 - gi|62088048|dbj|BAD92471.1| Isoleucyl-tRNA synthetase, cytoplasmic variant [Homo sapiens]
906.0 [0..4] [1063..27]
gi|40352733, gi|... - gi|40352733|gb|AAH64686.1| MGC68929 protein [Xenopus laevis], gi|148234431|ref|NP_001084397.1| hypot...
898.0 [0..2] [1063..8]

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Predicted Domain #1
Region A:
Residues: [1-834]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFNVPKEEE KIVEFWREID AFHTQLKLSQ GRPTYTFFDG PPFATGRPHH GHLLASTIKD  60
   61 SVTRYACLKG YHVERRFGWD THGLPVEHEI DKKLGITGSD DVMAMGIDKY NAECRKIVMT 120
  121 YASEWRATVE RLGRWIDFDN DYKTLYPSFM ESVWWVFKEL HTKGKVYRGY RVMPYSTACT 180
  181 TPLSNFEAQQ NYKEVPDPAI VVAFQSISDP EVSFLAWTTT PWTLPSNLAL AVHPDLQYIK 240
  241 ILDKDSNKKY ILMESCLGIL YKNPKKANFE ILERFQGKAL DGQKYEPLFP YFKSTFGERA 300
  301 FKLYSADYVE EGSGTGIVHQ APAFGEADYD AAWAAGIIDA DHQPPCPVDE QGLLTSEITD 360
  361 FAGQYVKDAD KEIIRSLKAS GHLVKHSQIF HSYPFCWRSD TPLIYRAVPS WFVRVKEITN 420
  421 EMVENVMSTH WVPQNIRDKR FANWLKNARD WNISRNRYWG TPIPLWVSDD YEEVVCIGSI 480
  481 KELEELSGVS NITDIHRDSI DHITIPSKKG KGTLHRVSEV FDCWFESGSM PYASRHYPFE 540
  541 RIEEFKHGFP ADFISEGVDQ TRGWFYTLTV LGTLLFDKAP YKNVIVSGLV MAEDGKKMSK 600
  601 RLKNYPEPNL IIEKYGSDAL RLYLINSPVV RAEILKFKED GVREVVTRVL IPWWNSYKFF 660
  661 EAQAALYKKV TGKDFVFDDA ATLSSNVMDR WILARCQSLI GFVDEEMKQY RLYTVVPQLL 720
  721 GLIEEMTNWY IRFNRRRLKG EDGEIETINA LNVLFEVLFT LVRIMGPFTP FITENIYQHL 780
  781 RNYMPIDKNE ISLRSVHFLP FPTYKSELDD ETVLRRVKRM QTIIELARYV REQN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1ileA
Description: ISOLEUCYL-TRNA SYNTHETASE
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [835-959]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NISLKTPLKT LIVILTNEEY LEDAKLLERY IAEELNVREV VFTSNEEKYG VVYSVQADWP  60
   61 VLGKKLRKDM ARVKKALPNV TSEEVKEFQK NKKMVLDGIE LVEGDLQIIR SVEVKNEFLK 120
  121 SNTDG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.39794
Match: 1rqgA
Description: Methionyl-tRNA synthetase from Pyrococcus abyssi
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [960-1064]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ICIVLLDIEI DAQLQAEGLA REVINRVQRL RKKSNLQVTD DVRMTYKIKN DTIGLESAVD  60
   61 SNEALFSKVL RRPIEKETGA DESNIIASEE QDVQGATFLL SLLRL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.926 d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.609 d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.563 d.323.1 Description not found.
View Download 0.539 d.208.1 MTH1598-like
View Download 0.536 d.241.2 Description not found.
View Download 0.531 d.208.1 MTH1598-like
View Download 0.528 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.523 a.4.5 "Winged helix" DNA-binding domain
View Download 0.379 d.110.4 SNARE-like
View Download 0.326 d.52.7 Ribosome-binding factor A, RbfA
View Download 0.295 d.110.4 SNARE-like
View Download 0.293 d.110.4 SNARE-like
View Download 0.265 d.80.1 Tautomerase/MIF


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