YRC Public Data Repository - Protein Structure Prediction

Protein:	sin1
Organism:	Schizosaccharomyces pombe
Length:	665 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sin1.

Description	E-value	Query Range	Subject Range
gi\|5002385, gi\|1... - gi\|5002385\|gb\|AAD37449.1\|AF155208_1 stress activated MAP kinase interacting protein [Schizosaccharom...	908.0	[0..16]	[665..1]
gi\|49097962, gi\|... - gi\|67540268\|ref\|XP_663908.1\| hypothetical protein AN6304.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	476.0	[0..204]	[662..312]
SIN1_MOUSE - Target of rapamycin complex 2 subunit MAPKAP1 OS=Mus musculus GN=Mapkap1 PE=1 SV=1	458.0	[0..166]	[651..68]
SIN1_RAT - Target of rapamycin complex 2 subunit MAPKAP1 OS=Rattus norvegicus GN=Mapkap1 PE=2 SV=1	458.0	[0..166]	[651..68]
ENSPTRT00000039534 - null MAPKAP1 - mitogen-activated protein kinase associated protein 1	456.0	[0..166]	[651..68]
gi\|46122163, gi\|... - gi\|46122163\|ref\|XP_385635.1\| hypothetical protein FG05459.1 [Gibberella zeae PH-1], gi\|42552433\|gb\|E...	455.0	[0..248]	[658..325]
gi\|55726571 - gi\|55726571\|emb\|CAH90052.1\| hypothetical protein [Pongo abelii] SIN1_PONAB - Target of rapamycin complex 2 subunit MAPKAP1 OS=Pongo abelii GN=MAPKAP1 PE=2 SV=1	452.0	[0..166]	[651..68]
SIN1_SHEEP - Target of rapamycin complex 2 subunit MAPKAP1 OS=Ovis aries GN=MAPKAP1 PE=1 SV=1	450.0	[0..166]	[651..68]

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Predicted Domain #1

Region A:
Residues: [1-253]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELTREKVLL LTFLRMQYSH ILPDSIENRV ISTEAPEWEL DKSLQDLLIH DYDYSKTSFS  60
   61 SSPPIVANDT VSNVRKPSDT KQVNGAGGQV NHSRAEDSDY ATSDLSESSD VGDDDNSCIF 120
  121 SFSKVPMQKD VASIKEEERL DPKISTLNNI DAIANLKLTN MVESSQAVNL TSSKQSSINQ 180
  181 QSSVSTDYDD LRSISEESFH LSQGEIPLTF PMNSSLTDTE ADAVVAVDAL FPGKQRGTHN 240
  241 TVNKARSVSN AKA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.04
Match:	1h1kI
Description:	THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [254-397]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTSALRALLE HKENSSQNGP LAENFATFSG HAESNALRLN IYFPSSESPS KPLFVELRKN  60
   61 VLVSEAIGYI LLQYVNQQLV PPIEDEAQNP NYWNLRIVED DGELDEDFPA LDRVGPLSKF 120
  121 GFDAFALVKA TPAQIKENQA AYPF

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [398-521]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSKHPTSIPE ANNKTHIRHT SSTSSQSQKQ AQDVKDTLNT SHVVQVRLPP YGDNARFCNI  60
   61 EISKTTRLAM VLNQVCWMKQ LERFKYTLRV AGSDTVLPLD KTFSSLDGNP TLELVKKKVR 120
  121 DKKG

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.6
Match:	2al3A
Description:	No description for 2al3A was found.

Predicted Domain #4

Region A:
Residues: [522-665]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STQQLPTSSP QNSVYGSIKK DAQSSTYNAT DIMSSNTYQE FLVWKRQPVS FMGRHERLLA  60
   61 IDGEYVHIMP SESKNIFETP KTSSIHAGSI ILCKQSKKSP CNFKMIVSKN RETKRYDFEV 120
  121 LSALEAAIIV SRIRALMNTV KKIN

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.12
Match:	1p6sA
Description:	Solution Structure of the Pleckstrin Homology Domain of Human Protein Kinase B beta (Pkb/Akt)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits