YRC Public Data Repository - Protein Structure Prediction

Protein:	sec6
Organism:	Schizosaccharomyces pombe
Length:	730 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sec6.

Description	E-value	Query Range	Subject Range
EXOC3 - exocyst complex component 3	613.0	[0..9]	[725..22]
gi\|114598823 - gi\|114598823\|ref\|XP_517603.2\| PREDICTED: Sec6 protein [Pan troglodytes]	612.0	[0..9]	[725..11]
gi\|55730539 - gi\|55730539\|emb\|CAH91991.1\| hypothetical protein [Pongo abelii] gi\|197102172 - gi\|197102172\|ref\|NP_001126156.1\| exocyst complex component 3 [Pongo abelii]	612.0	[0..9]	[725..11]
gi\|47847438 - gi\|47847438\|dbj\|BAD21391.1\| mFLJ00157 protein [Mus musculus]	607.0	[0..9]	[725..36]
gi\|109076604 - gi\|109076604\|ref\|XP_001094786.1\| PREDICTED: Sec6 protein isoform 2 [Macaca mulatta]	606.0	[0..9]	[725..11]
EXOC3_RAT - Exocyst complex component 3 OS=Rattus norvegicus GN=Exoc3 PE=1 SV=1	598.0	[0..9]	[725..21]
gi\|74003058 - gi\|74003058\|ref\|XP_848639.1\| PREDICTED: similar to SEC6-like 1 isoform 3 [Canis familiaris]	582.0	[0..9]	[725..11]

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Predicted Domain #1

Region A:
Residues: [1-265]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAAASDDAV YNKVADILRQ CEDFHRLSTH IERFEREQAS LNMHVKTELE KHVEAVEMLT  60
   61 LCESAREMVD EFPLISRMSR IYKNCYATKQ MISQLNNLVK ETDVIEDMLR EDLELDSDMP 120
  121 NLLRAHYKLS KLREFREEAL YQASLEGQSD LPITLENSFS NLNTLSDNFD RLVLNFCRNI 180
  181 FQLVKSGHIK TIVQIFKIVE AEESSDEVLK SIRDAKSSLP DSQDGPFLSL QGMTRQLRNF 240
  241 RLRVLEEFQG AAAENFQRAW VSYLE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.69897
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [266-336]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGSGELNLDF IFEDLKVAFY VLPDLTPPSY NIAKTFASIY QECLVGLVTK AVSLDTPAAV  60
   61 YLYLINFHRE Y

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [337-730]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKFFEENAPF SVDEVEPGLE DGKDGILVRE YTRLFTQKIR EWSDKLFQSS VDTFMKRESE  60
   61 PELDSDGNYG LQGTIIFFQM ITQQINIISH TNNSDVVGIV LSSIMYIMQS MQDQWKSVMR 120
  121 SELSQQLSGN PESVPPGLME YLLAVANDNL KCAGFMDNTL LNTFELITSE REEDLREAFG 180
  181 KTVDGYILIS DIGVSQIVAI ISNDVKPALT SLFQPNWYQS SNMKLIVDTF RDYIVDCIEH 240
  241 MVPGLFDVFL LEASNALTIS YLRSIFNKNA CFDGDNAIQQ IRSDIALAIR VFGEYMAAEH 300
  301 LRSTFEPIEK LLLGMLDADV ETVSEYFHLL KEAYWDAPLS LVEAVLQNRT DLEKSIIKKM 360
  361 IDIVRHENDS LQIDTSQQPT VFSQVTSLSG SSIL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	85.30103
Match:	2fji1
Description:	No description for 2fji1 was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits