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View Structure Prediction Details

Protein: sec15
Organism: Schizosaccharomyces pombe
Length: 785 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sec15.

Description E-value Query
Range
Subject
Range
gi|114631863 - gi|114631863|ref|XP_507926.2| PREDICTED: SEC15-like 1 [Pan troglodytes]
919.0 [0..4] [783..133]
gi|109089962 - gi|109089962|ref|XP_001088450.1| PREDICTED: SEC15-like 1 [Macaca mulatta]
919.0 [0..4] [783..134]
gi|9507077, gi|7... - gi|9507077|ref|NP_062150.1| SEC15-like 1 [Rattus norvegicus], gi|7513970|pir||T09221 exocyst complex...
909.0 [0..4] [783..31]
EXOC6 - exocyst complex component 6
905.0 [0..4] [783..13]
gi|74195820, gi|... - gi|74199032|dbj|BAE30731.1| unnamed protein product [Mus musculus], gi|74195820|dbj|BAE30472.1| unna...
902.0 [0..4] [783..13]
gi|73980553 - gi|73980553|ref|XP_866644.1| PREDICTED: similar to Exocyst complex component Sec15A isoform 3 [Canis...
901.0 [0..3] [783..16]

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Predicted Domain #1
Region A:
Residues: [1-189]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIDVLEFVD KIASIESAGD TLDRLPQLIS LACEKGQETQ VYERLNELAS KSAIRVEQLS  60
   61 AENNQDFSKS VNQLSVVRSE LRSLQSLMAD LNTDIQASGR DLQNMKQQLN SLSTSERFLT 120
  121 KYHNLVRSCM QVLHQVQYSQ ELLSKKQYLP TLRICSEISE VHLKRLDGLG MYSTIQQYIV 180
  181 TTKEAICSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.39794
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [190-263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VMEDLHEWLF SIRQKLPLVG KSCSQQIDEA RRRWAREYKE DLVNLSSKTS ISLELYLLEM  60
   61 MDFSPLDNEI VKIS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [264-360]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FEPLYICLQV HSYLGLLSSF RSSFERDRRR QQEFLAPKSL TTLDMAVVSE WLNSIAGFMI  60
   61 VEYYILQCIP NFRSYEEVQN IWTIICEKLV ETILSVA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.875 0.023 vesicle docking during exocytosis f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore

Predicted Domain #4
Region A:
Residues: [361-706]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTEQSTTTII KLKNQIVLLM HTMERFGFSV ESLRNLCVEL IDAFGGALIL KHSVFFEEAF  60
   61 EKDVYAPMIV ETQEEYDHYI APYWNFPSEP FPRTMSFSKM CPLCCTTLSK FVRHFFMFLN 120
  121 DSVILATEVN EKAPRFYRRF ILRSLVDRLK SLYPKLALSQ MSQLVKNFYA FEDPLLQIEK 180
  181 SLVLNKPIHQ IGAEASSSNN VKSTELLEGL ANARKSALHE IFVKINLKID DFLGLAEYDW 240
  241 TTTQVRKDVS GYLQEMVTYL QTMYLESLAG LPKHDKSYVY LETLDHLCTA MVDLLSDPSI 300
  301 RKVTTAAAEG FKLDVEYLES FAAQVPDQSI VNADSFIELR QCANLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 95.69897
Match: 2a2fX
Description: Crystal Structure of Sec15 C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [707-785]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGDNMEEYLD TDKFMRDFNR LQPAVAIKFL ERYNIPACLQ DNFTNLLCRH INNYSANPLS  60
   61 NDRPKRRAIE ILIATLKKR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle