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View Structure Prediction Details

Protein: smc6
Organism: Schizosaccharomyces pombe
Length: 1140 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for smc6.

Description E-value Query
Range
Subject
Range
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
334.0 [0..4] [987..1925]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
296.0 [0..4] [973..923]
MYH4_MOUSE - Myosin-4 OS=Mus musculus GN=Myh4 PE=2 SV=1
296.0 [0..4] [973..925]
MYH4_RAT - Myosin-4 OS=Rattus norvegicus GN=Myh4 PE=1 SV=1
295.0 [0..4] [973..925]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
295.0 [0..4] [973..924]
gi|50757613 - gi|50757613|ref|XP_415578.1| PREDICTED: similar to myosin heavy chain [Gallus gallus]
295.0 [0..4] [973..872]
MYH2_HORSE - Myosin-2 OS=Equus caballus GN=MYH2 PE=2 SV=1
295.0 [0..4] [973..923]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTELTNVSL EEAITEKTSE NRRKRDSDVL QTEEVDLSNV KRIRASRNQD NRPERQSRLQ  60
   61 RSSSLIEQVR GNEDGENDVL NQTRETNSNF DNRV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [95-248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVIECIHLVN FMCHDSLKIN FGPRINFVIG HNGSGKSAIL TGLTICLGAK ASNTNRAPNM  60
   61 KSLVKQGKNY ARISVTISNR GFEAYQPEIY GKSITIERTI RREGSSEYRL RSFNGTVIST 120
  121 KRDELDNICD HMGLQIDNPM NILTQDTARQ FLGN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.39794
Match: 1w1wA
Description: Sc Smc1hd:Scc1-C complex, ATPgS
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [249-632]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSPKEKYQLF MKGIQLKQLE ENYSLIEQSL INTKNVLGNK KTGVSYLAKK EEEYKLLWEQ  60
   61 SRETENLHNL LEQKKGEMVW AQVVEVEKEL LLAEKEFQHA EVKLSEAKEN LESIVTNQSD 120
  121 IDGKISSKEE VIGRAKGETD TTKSKFEDIV KTFDGYRSEM NDVDIQKRDI QNSINAAKSC 180
  181 LDVYREQLNT ERARENNLGG SQIEKRANES NNLQREIADL SEQIVELESK RNDLHSALLE 240
  241 MGGNLTSLLT KKDSIANKIS DQSEHLKVLE DVQRDKVSAF GKNMPQLLKL ITRETRFQHP 300
  301 PKGPMGKYMT VKEQKWHLII ERILGNVING FIVRSHHDQL ILKELMRQSN CHATVVVGKY 360
  361 DPFDYSSGEP DSQYPTVLKI IKFD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.522879
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [633-713]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDEVLHTLIN HLGIEKMLLI EDRREAEAYM KRGIANVTQC YALDPRNRGY GFRIVSTQRS  60
   61 SGISKVTPWN RPPRIGFSSS T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [714-967]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIEAEKKILD DLKKQYNFAS NQLNEAKIEQ AKFKRDEQLL VEKIEGIKKR ILLKRREVNS  60
   61 LESQELSVLD TEKIQTLERR ISETEKELES YAGQLQDAKN EEHRIRDNQR PVIEEIRIYR 120
  121 EKIQTETQRL SSLQTELSRL RDEKRNSEVD IERHRQTVES CTNILREKEA KKVQCAQVVA 180
  181 DYTAKANTRC ERVPVQLSPA ELDNEIERLQ MQIAEWRNRT GVSVEQAAED YLNAKEKHDQ 240
  241 AKVLVARLTQ LLQA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.13
Match: 1c1gA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [968-1140]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEETLRRRNE MWTKFRKLIT LRTKELFELY LSQRNFTGKL VIKHQEEFLE PRVYPANRNL  60
   61 ATAHNRHEKS KVSVQGLSGG EKSFATICML LSIWEAMSCP LRCLDEFDVF MDAVNRLVSI 120
  121 KMMVDSAKDS SDKQFIFITP QDMGQIGLDK DVVVFRLSDP VVSSSALPPS TAP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 2pzeA
Description: No description for 2pzeA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle