YRC Public Data Repository - Protein Structure Prediction

Protein:	ade5
Organism:	Schizosaccharomyces pombe
Length:	207 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ade5.

Description	E-value	Query Range	Subject Range
gi\|77958968 - gi\|77958968\|ref\|ZP_00822993.1\| COG0299: Folate-dependent phosphoribosylglycinamide formyltransferase...	208.0	[0..1]	[205..1]
gi\|85694914, gi\|... - gi\|85711413\|ref\|ZP_01042472.1\| Folate-dependent phosphoribosylglycinamide formyltransferase [Idiomar...	208.0	[0..2]	[205..1]
gi\|157126853, gi... - gi\|157126853\|ref\|XP_001660978.1\| phosphoribosylamine-glycine ligase [Aedes aegypti], gi\|108873132\|gb...	206.0	[0..2]	[205..1170]
gi\|46849487 - gi\|46849487\|dbj\|BAD17953.1\| glycinamide ribonucleotide synthetase-aminoimidazole ribonucleotide synt...	205.0	[0..4]	[206..805]
gi\|77960046, gi\|... - gi\|77960046\|ref\|ZP_00823945.1\| COG0299: Folate-dependent phosphoribosylglycinamide formyltransferase...	205.0	[0..2]	[205..1]
gi\|88795665, gi\|... - gi\|88795665\|ref\|ZP_01111358.1\| phosphoribosylglycinamide formyltransferase [Alteromonas macleodii 'D...	203.0	[0..4]	[205..7]
gi\|115968704, gi... - gi\|115968704\|ref\|XP_001190560.1\| PREDICTED: similar to glycinamide ribonucleotide synthetase-aminoim...	203.0	[0..2]	[206..808]
gi\|89080493, gi\|... - gi\|89095239\|ref\|ZP_01168161.1\| phosphoribosylglycinamide formyltransferase [Oceanospirillum sp. MED9...	202.0	[0..1]	[205..1]
gi\|46849393 - gi\|46849393\|dbj\|BAD17906.1\| glycinamide ribonucleotide synthetase-aminoimidazole ribonucleotide synt...	201.0	[0..4]	[205..796]
gi\|71145720, gi\|... - gi\|71279980\|ref\|YP_269893.1\| phosphoribosylglycinamide formyltransferase [Colwellia psychrerythraea ...	201.0	[0..1]	[204..1]

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Predicted Domain #1

Region A:
Residues: [1-207]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVASLVVLIS GSGSNLQAII DATLNGVLKG EAAVTHVLSN RKNAYGLERA AKAGIPTSLH  60
   61 TLLPYKKEYG PEIGRKKYDA ELAEKIIKLQ PSLVVCAGWM HILSPEVLIP LETNKIGIIN 120
  121 LHPALPGAFN GIHAIERAFE AAQQGKITHT GAMVHWVIAA VDEGKPIIVQ EVPILSTDSI 180
  181 EALEEKIHAA EHVILVQAIH QIITDNK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.39794
Match:	1c3eA
Description:	Glycinamide ribonucleotide transformylase, GART
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	4.09881190860822	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.01667310557403	bayes_pls_golite062009
hydroxymethyl-, formyl- and related transferase activity	3.81159871979977	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	3.49010887242285	bayes_pls_golite062009
phosphoribosylglycinamide formyltransferase activity	2.94311083909314	bayes_pls_golite062009
methionyl-tRNA formyltransferase activity	2.39150724300118	bayes_pls_golite062009
catalytic activity	2.16003793103722	bayes_pls_golite062009
binding	1.1813924954238	bayes_pls_golite062009
transferase activity	1.01502594768782	bayes_pls_golite062009
ligase activity	0.922788719307786	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: