YRC Public Data Repository - Protein Structure Prediction

Protein:	pho4
Organism:	Schizosaccharomyces pombe
Length:	463 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pho4.

Description	E-value	Query Range	Subject Range
SPBC21H7.03c - acid phosphatase PPA3_SCHPO - Thiamine-repressible acid phosphatase SPBC21H7.03c OS=Schizosaccharomyces pombe (strain 972 / ATCC 2...	400.0	[0..1]	[463..1]
PHYB_EMENI - 3-phytase B precursor (EC 3.1.3.8) (Myo-inositol-hexaphosphate 3-phosphohydrolase B) (3 phytase B) (...	360.0	[0..7]	[448..13]
PHYB_EMENI - 3-phytase B OS=Emericella nidulans GN=phyB PE=3 SV=2 PHYB_EMENI - 3-phytase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=p...	358.0	[0..7]	[448..13]
gi\|134058627, gi... - gi\|4185610\|dbj\|BAA74433.1\| phytase [Aspergillus niger], gi\|134058627\|emb\|CAK38611.1\| phytase phyA-As... gi\|145257388 - gi\|145257388\|ref\|XP_001401713.1\| phytase phyA-Aspergillus niger	358.0	[0..1]	[449..10]
gi\|75863998 - gi\|75863998\|gb\|ABA29207.1\| phytase [Aspergillus awamori]	357.0	[0..1]	[449..10]
gi\|11992745 - gi\|11992745\|gb\|AAG40885.1\| phytase [Aspergillus ficuum]	356.0	[0..1]	[449..10]
gi\|23344720, gi\|... - gi\|27261395\|gb\|AAN86079.1\| phytase [synthetic construct], gi\|23344720\|gb\|AAN28673.1\| phytase [synthe...	355.0	[0..13]	[449..2]
gi\|47176936 - gi\|47176936\|gb\|AAT12504.1\| phytase; myo-inostol hexakisphosphate phosphohydrolase [Aspergillus oryza...	355.0	[0..13]	[449..2]

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Predicted Domain #1

Region A:
Residues: [1-463]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLSGISLWL LAASIVHAGK SQFEAFENEF YFKDHLGTIS VYHEPYFNGP TTSFPESCAI  60
   61 KQVHLLQRHG SRNPTGDDTA TDVSSAQYID IFQNKLLNGS IPVNFSYPEN PLYFVKHWTP 120
  121 VIKAENADQL SSSGRIELFD LGRQVFERYY ELFDTDVYDI NTAAQERVVD SAEWFSYGMF 180
  181 GDDMQNKTNF IVLPEDDSAG ANSLAMYYSC PVYEDNNIDE NTTEAAHTSW RNVFLKPIAN 240
  241 RLNKYFDSGY NLTVSDVRSL YYICVYEIAL RDNSDFCSLF TPSEFLNFEY DSDLDYAYWG 300
  301 GPASEWASTL GGAYVNNLAN NLRKGVNNAS DRKVFLAFTH DSQIIPVEAA LGFFPDITPE 360
  361 HPLPTDKNIF TYSLKTSSFV PFAGNLITEL FLCSDNKYYV RHLVNQQVYP LTDCGYGPSG 420
  421 ASDGLCELSA YLNSSVRVNS TSNGIANFNS QCQAHSTNVT VYY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	77.69897
Match:	1qfxA
Description:	Phytase (myo-inositol-hexakisphosphate-3-phosphohydrolase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acid phosphatase activity	4.64587359284617	bayes_pls_golite062009
phosphatase activity	1.82804953813502	bayes_pls_golite062009
hydrolase activity	1.79174542059681	bayes_pls_golite062009
phosphoric ester hydrolase activity	1.63930771076865	bayes_pls_golite062009
catalytic activity	1.37714494241232	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.01761355562415	bayes_pls_golite062009
kinase activity	0.891791120150528	bayes_pls_golite062009
binding	0.876312809995654	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.803890819223102	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.57794482374484	bayes_pls_golite062009
intramolecular transferase activity	0.17180601190736	bayes_pls_golite062009
protein binding	0.136916442724833	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: