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View Structure Prediction Details

Protein: pcp1
Organism: Schizosaccharomyces pombe
Length: 1208 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pcp1.

Description E-value Query
Range
Subject
Range
gi|42476190, gi|... - gi|42476190|ref|NP_060004.2| myosin, heavy polypeptide 2, skeletal muscle, adult [Homo sapiens], gi|...
419.0 [0..18] [1204..761]
gi|76643975 - gi|76643975|ref|XP_883032.1| PREDICTED: similar to Myosin-8 (Myosin heavy chain, skeletal muscle, pe...
419.0 [0..18] [1204..758]

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Predicted Domain #1
Region A:
Residues: [1-490]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSERDFNTQS PKFKDENANS VISQSDFLGK SLKNNNDDYS DFRGSYLNDK SSFQTPLRNG  60
   61 SYQPKGSLEF TPLLQSSNKN SDKYNGSLGD KGSFDPNSYG LSAISKQATQ EALSISQGND 120
  121 SYDVSKLTDL SKNSEIDHTD GELPANAALT LREQEKVLEK VSRENFGLRI KIVCLEKRLE 180
  181 SMAPEQIKEA VKDNVELHAE RANLQLQLKR TESLLQKSED KNFKLEEKVD YLSKVNDVEQ 240
  241 SQNVKVFTER IRFLENALEK VQREKDSLST EMEEDKSNKE VDYEYEIRQL QNRLDELSEE 300
  301 LDVAQDLLTE KEDEIATLKR QIEEKENSSS AFENEENSSY VHLQEDYAIL QAKCDEFADR 360
  361 IQVLTADLEK EKENQIMHES EASIGLTDSM QVHTLQEQLH KANEEIEFLH DQISRMNEEG 420
  421 KNFEDIMLQF RSLEEERDVL ESKLQTLEDD NNSLRLMTSS LGNQIESLRT QNREIDEEKN 480
  481 HLRLLASKNS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.522879
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [491-552]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKALAETNIR LQEVTKELET LRMKNSNDLN EIHDLREENE GLTLKIDSIT KEKDRLINEL  60
   61 EQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [553-849]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RIKSYEVNVS ELNGTIDEYR NKLKDKEETY NEVMNAFQYK DNDLRRFHES INKLQDREKE  60
   61 LTSNLEKKNL VISSLRETVA MLEKERESIK KYLSGNAKDL DNTNLMEILN DKISVLQRQL 120
  121 TDVKDELDVS EEEREEAIVA GQKLSASFEL MSNEKQALEL KYSSLKNELI NAQNLLDRRE 180
  181 EELSELSKKL FEERKIRSGS NDDIEKNKEI NVLNSELADK LAQIRHLESD KMELDKLVHH 240
  241 LNRGIEEANI EENAVKKRLC LLMGCDYSSV SILQIVSQIE HFVNQQIQTI RSLKQEL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.81
Match: 1c1gA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [850-1208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RHDFVQFSGK KEQELSRSFE KFGLGTETKH DILAQRNRNV SEKMNDLENA AQKFFSSPDR  60
   61 KNGYLYPSEH TSKIEYLEKT IEDLKLALQD ELKNRNLLMD DISSYNKQTT KLQEKIKWLE 120
  121 RERSILIDEL ESYRSNQFNY QNNLVQDKNE LEERLKEIQK ELEVYNNHFM KQAELMTSNV 180
  181 TDESQLMLKT LREALQSKTN NIDHLSTILE RNRKEYKSLL DDYNQLRARY KNLQSNTPQS 240
  241 TQSGQYESEI KGLSKLTKYL QSKCRREHSL RLDLAFSKKF ILMQLTGYET CNKINLRMLQ 300
  301 KIGISPDPDL SKKHIKLKSL IIVVCSIERM KRMKNEWLKQ AQLKQSLQRA AAKAKTANY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.69897
Match: 2tmaA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle