YRC Public Data Repository - Protein Structure Prediction

Protein:	arg3
Organism:	Schizosaccharomyces pombe
Length:	327 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for arg3.

Description	E-value	Query Range	Subject Range
OTC_PYRAB - Ornithine carbamoyltransferase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=argF PE=3 SV=4 OTC_PYRAB - Ornithine carbamoyltransferase OS=Pyrococcus abyssi GN=argF PE=3 SV=4	440.0	[0..1]	[317..1]
OTC_PYRHO - Ornithine carbamoyltransferase OS=Pyrococcus horikoshii GN=argF PE=3 SV=3 OTC_PYRHO - Ornithine carbamoyltransferase OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 /...	439.0	[0..1]	[317..1]
OTC_PYRFU - Ornithine carbamoyltransferase OS=Pyrococcus furiosus GN=argF PE=1 SV=6 OTC_PYRFU - Ornithine carbamoyltransferase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1...	437.0	[0..1]	[317..1]
OTC_THEKO - Ornithine carbamoyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)... OTC_PYRKO - Ornithine carbamoyltransferase OS=Pyrococcus kodakaraensis GN=argF PE=3 SV=1	436.0	[0..1]	[317..1]
OTC_PYRFU - (Q51742) Ornithine carbamoyltransferase (EC 2.1.3.3) (OTCase)	434.0	[0..3]	[317..2]
gi\|196197763, gi... - gi\|196252829\|ref\|ZP_03151478.1\| ornithine carbamoyltransferase [Clostridium thermocellum DSM 4150], ... gi\|67849267, gi\|... - gi\|67916777\|ref\|ZP_00510472.1\| Ornithine carbamoyltransferase [Clostridium thermocellum ATCC 27405],...	427.0	[0..9]	[318..3]
gi\|83591107, gi\|... - gi\|83591107\|ref\|YP_431116.1\| ornithine carbamoyltransferase [Moorella thermoacetica ATCC 39073], gi\|...	423.0	[0..1]	[316..4]

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Predicted Domain #1

Region A:
Residues: [1-327]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFKKFPRHL LSIRDLSRGE IVKLIDRSSE IKQAYKQNFQ NRRSVQMSGL SSQNVAMIFS  60
   61 KRSTRTRVSV ESAVSCLGGN AMFLGKDDIQ LGVNESLYDT SKVISSMVSG IVARVNKYSD 120
  121 VATLAKHASC PVINGLCDTF HPLQALADLL TIKETFKSFD GLKVAWVGDA NNVLHDLMIA 180
  181 NAKVGIHTSV AKPKDVNVRD DILSIVNEAA NENGSTFEIV NDPKVAVKNA DIVVTDTWIS 240
  241 MGQEAEKEQR LKQFTGFQVT GEIMKLAKPS CKFMHCLPRH PEEVSDEVFY GENSLVFQEA 300
  301 ENRKWTTVAV LEALLVNRGE ILPPASA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	123.0
Match:	1pvvA
Description:	Refined Structure of Pyrococcus furiosus Ornithine Carbamoyltransferase at 1.87 A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ornithine carbamoyltransferase activity	6.08861672645671	bayes_pls_golite062009
carboxyl- or carbamoyltransferase activity	5.32518877756022	bayes_pls_golite062009
aspartate carbamoyltransferase activity	3.84118892938517	bayes_pls_golite062009
transferase activity	2.2887439598954	bayes_pls_golite062009
carbamoyl-phosphate synthase activity	2.21516900257798	bayes_pls_golite062009
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	2.19154218663721	bayes_pls_golite062009
catalytic activity	2.06069688716378	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.54712264845123	bayes_pls_golite062009
binding	1.00470116390248	bayes_pls_golite062009
dihydroorotase activity	0.585784960037124	bayes_pls_golite062009
protein binding	0.171217252293449	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: