YRC Public Data Repository - Protein Structure Prediction

Protein:	met11
Organism:	Schizosaccharomyces pombe
Length:	641 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for met11.

Description	E-value	Query Range	Subject Range
gi\|3702200 - gi\|3702200\|emb\|CAA09738.1\| methylenetetrahydrofolate reductase [Schizosaccharomyces pombe]	876.0	[0..1]	[641..1]
gi\|42554286, gi\|... - gi\|46136113\|ref\|XP_389748.1\| hypothetical protein FG09572.1 [Gibberella zeae PH-1], gi\|42554286\|gb\|E...	820.0	[0..1]	[638..1]
gi\|38110342, gi\|... - gi\|39952171\|ref\|XP_363802.1\| hypothetical protein MG01728.4 [Magnaporthe grisea 70-15], gb\|EAA56077....	816.0	[0..1]	[638..1]
gi\|88180522, gi\|... - gi\|88180522\|gb\|EAQ87990.1\| conserved hypothetical protein [Chaetomium globosum CBS 148.51], gi\|11619...	814.0	[0..1]	[638..1]
gi\|46100189, gi\|... - gi\|71021057\|ref\|XP_760759.1\| hypothetical protein UM04612.1 [Ustilago maydis 521], ref\|XP_402227.1\| ...	803.0	[0..2]	[638..18]
gi\|67539426, gi\|... - gi\|67539426\|ref\|XP_663487.1\| hypothetical protein AN5883.2 [Aspergillus nidulans FGSC A4], ref\|XP_41... gi\|113911583 - gi\|113911583\|gb\|ABI48273.1\| methylenetetrahydrofolate reductase [Emericella nidulans]	803.0	[0..1]	[639..1]
orf19.5321, orf1... - orf19.5321 CGDID:CAL0004277 Assembly 19, Contig19-10225 (78816, 76894) CDS, reverse complemented, tr... gi\|46438742, gi\|... - gi\|68477786\|ref\|XP_717045.1\| methylenetetrahydrofolate reductase-like protein [Candida albicans SC53...	797.0	[0..3]	[640..4]
gi\|71001564, gi\|... - gi\|71001564\|ref\|XP_755463.1\| methylenetetrahydrofolate reductase [Aspergillus fumigatus Af293], gi\|6...	793.0	[0..1]	[638..1]
MTHR_ORYSA - Probable methylenetetrahydrofolate reductase (EC 1.5.1.20) - Oryza sativa (Rice) gi\|125546191 - gi\|125546191\|gb\|EAY92330.1\| hypothetical protein OsI_14054 [Oryza sativa Indica Group] MTHR_ORYSJ - Probable methylenetetrahydrofolate reductase OS=Oryza sativa subsp. japonica GN=Os03g0815200 PE=2 SV...	792.0	[0..1]	[639..1]

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Predicted Domain #1

Region A:
Residues: [1-304]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIVDLIDKI PNGNAFYSFE YFPPKTTVGL ENLSSRITRM SRNMMPLFSS VTWGTAGSTA  60
   61 EVSIYLAKML EQHHKIPACL HLTCTNVDKA IIDKALETAK EYGIRNILAL RGDPPLNSDH 120
  121 WEGKVSEFEH AVDLVRYIRE KYGDYFCIGV AAYPEGHVDS NVPELSKDPL RDIPFLIEKV 180
  181 EAGADFIITQ IFYEPEAFIK FENFVRNHSS NALRNIPIIP AIMPIQSYGS LKRMTRLCGC 240
  241 SVPSSLMQRL NAAKPDDEAI KNIGVEHIVD MIKKIMDNVQ GRVHGFHFCT LNLERSVALI 300
  301 LKNS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	97.0
Match:	1v93A
Description:	5,10-Methylenetetrahydrofolate Reductase from Thermus thermophilus HB8
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [305-505]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLLTKRWKQV ESEMEDEKLL RTTRKRLSLD EPAELHNQVV VPSQQPVADK SSNLFVTSKQ  60
   61 SSVSGHKDNL TEEAPFSVSE GSGVLGRQAN WDDFTNGRFG DPRSPAYGEI DGYGPTLHFP 120
  121 PSEALKLWGY PVDESDITSL FQKHIMSDIS AIPWIDEPVE VETKTIAKYL LKLNGNSWWT 180
  181 VGSQPAVNGA PSADPVFGWG P

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [506-641]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGGRVFQKAF VECFVNGKDL KDFITKWHDN PQVTYYAGNN KSEFLTNAPK DGASAVTWGV  60
   61 YPGREIIQST IIAEVSFKAW LSESFQVWGE WANLYSKNTP SRKLLENCIN DRWLVTVIHH 120
  121 DFMDKNGLWK VLEIDF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits