YRC Public Data Repository - Protein Structure Prediction

Protein:	mob1
Organism:	Schizosaccharomyces pombe
Length:	210 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mob1.

Description	E-value	Query Range	Subject Range
gi\|73975379 - gi\|73975379\|ref\|XP_539306.2\| PREDICTED: similar to Mps one binder kinase activator-like 1A (Mob1 hom...	362.0	[0..2]	[209..185]
MOL1B_PONPY - Mps one binder kinase activator-like 1B - Pongo pygmaeus (Orangutan) gi\|55606148 - gi\|55606148\|ref\|XP_515735.1\| PREDICTED: Mob4B protein isoform 4 [Pan troglodytes] tr\|G1SUR2\|G1SUR2... - Uncharacterized protein OS=Oryctolagus cuniculus GN=MOB1A PE=4 SV=2 MOB1A_MOUSE - MOB kinase activator 1A OS=Mus musculus GN=Mob1a PE=2 SV=3 MOBKL1B - MOB1, Mps One Binder kinase activator-like 1B (yeast) MOB1A_PONAB - MOB kinase activator 1A OS=Pongo abelii GN=MOB1A PE=2 SV=3 MOB1A_RAT - MOB kinase activator 1A OS=Rattus norvegicus GN=Mob1a PE=2 SV=3 gi\|111305145, gi... - gi\|76628940\|ref\|XP_871266.1\| PREDICTED: similar to Mob4B protein [Bos taurus], gi\|115496426\|ref\|NP_0... gi\|73980517 - gi\|73980517\|ref\|XP_852858.1\| PREDICTED: similar to Mob4B protein isoform 1 [Canis familiaris]	350.0	[0..2]	[209..3]
gi\|10435207 - gi\|10435207\|dbj\|BAB14525.1\| unnamed protein product [Homo sapiens]	349.0	[0..2]	[209..3]
gi\|109103421 - gi\|109103421\|ref\|XP_001107567.1\| PREDICTED: similar to Mob4B protein [Macaca mulatta]	349.0	[0..4]	[209..47]
gi\|114578135 - gi\|114578135\|ref\|XP_001154085.1\| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]	348.0	[0..4]	[209..47]
gi\|115313732, gi... - gi\|89269096\|emb\|CAJ81503.1\| MOB1, Mps One Binder kinase activator-like 1B [Xenopus tropicalis], gi\|6...	347.0	[0..2]	[209..3]
gi\|109484173, gi... - gi\|34856301\|ref\|XP_342714.1\| PREDICTED: similar to Mob4B protein [Rattus norvegicus], gi\|27730897\|re...	347.0	[0..2]	[209..3]
gi\|113549012, gi... - gi\|50901186\|ref\|XP_463026.1\| putative Mob1-like protein [Oryza sativa (japonica cultivar-group)], gi...	346.0	[0..1]	[210..3]

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Predicted Domain #1

Region A:
Residues: [1-210]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGFSNKTAK TFRVRKTEAG TKHYQLRQYA EATLGSGSLM EAVKLPKGED LNEWIAMNTM  60
   61 DFYTQINMLY GTITEFCTAA SCPQMNAGPS YEYYWQDDKI YTKPTRMSAP DYINNLLDWT 120
  121 QEKLDDKKLF PTEIGVEFPK NFRKVIQQIF RRLFRIYAHI YCSHFHVMVA MELESYLNTS 180
  181 FKHFVFFCRE FGLMDNKEYA PMQDLVDSMV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	86.39794
Match:	1r3bA
Description:	Solution structure of xenopus laevis Mob1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.92301852481284	bayes_pls_golite062009
kinase regulator activity	1.89112613830997	bayes_pls_golite062009
enzyme regulator activity	1.85961781963242	bayes_pls_golite062009
protein binding	1.70532605681329	bayes_pls_golite062009
protein kinase regulator activity	1.22656624834768	bayes_pls_golite062009
enzyme activator activity	1.01199608762933	bayes_pls_golite062009
kinase activator activity	0.48120280834988	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: