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View Structure Prediction Details

Protein: mis6
Organism: Schizosaccharomyces pombe
Length: 672 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mis6.

Description E-value Query
Range
Subject
Range
CENPI_MOUSE - Centromere protein I OS=Mus musculus GN=Cenpi PE=2 SV=1
682.0 [0..12] [529..63]
CENPI - centromere protein I
660.0 [0..12] [530..66]
gi|114689433 - gi|114689433|ref|XP_521177.2| PREDICTED: follicle-stimulating hormone primary response protein 1 [Pa...
650.0 [0..12] [530..66]
CENPI_RAT - Centromere protein I OS=Rattus norvegicus GN=Cenpi PE=2 SV=1
640.0 [0..12] [539..63]
gi|74008206 - gi|74008206|ref|XP_549138.2| PREDICTED: similar to follicle-stimulating hormone primary response pro...
636.0 [0..12] [530..178]
gi|109131540, gi... - gi|109131542|ref|XP_001092023.1| PREDICTED: similar to follicle-stimulating hormone primary response...
604.0 [0..12] [530..65]

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Predicted Domain #1
Region A:
Residues: [1-239]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESFENKGFL DIEEGIQWIK KNSENLSSSK KTILARLQQF HKLCSEVGLN QHSISSLLDV  60
   61 ILSKKTHFDK NHVQLLIKCL YPNELISQTI AIRIISSLDP HGLRCSYAIQ AKLLNWLIHV 120
  121 YEFLDGNNLL CRYYGVLFHF LDFLTLRPYI SNLLVLLTKH YHVKSFRIHQ LLALYQKPGN 180
  181 TADPYLLALI LTYKQHFPDV IVGSYTYRKH GSVRLDSEWI AATKAILNRQ SEDVPLETW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [240-436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSEKRKRQSS LIPDLITMKN TSSSYSLEEL TSVQQMGLVY EKIVFPSRIA AVLKSKLFLI  60
   61 FLFLKNKNVY YSRLDEWLHI TLNYGLALRS GSNNQEEEVL HLLYKYLLFS PKFPKSLLQY 120
  121 VITFFSKPNI TEENYNLLTL LVTHIPITTD SSYFNSLLKE FEQFILQKNA EFCSKHLNIL 180
  181 WLWLFRMLNL RIASMGN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [437-543]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NHTLLEKCLL ITNHATFLVS HFSWDVSLAY QLSRLFQLYY KILTKIRKQI EPNIPPKELI  60
   61 YVLFFQPSAF YINSMVGLLL LTKNYQERLM DSRIDAISKF THSYLKS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.817 a.29.13 Description not found.
View Download 0.777 a.29.16 Description not found.
View Download 0.735 a.29.13 Description not found.
View Download 0.681 a.219.1 Description not found.
View Download 0.564 d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.457 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.457 a.77.1 DEATH domain
View Download 0.406 a.7.8 GAT domain
View Download 0.305 d.54.1 Enolase N-terminal domain-like
View Download 0.274 a.16.1 S15/NS1 RNA-binding domain
View Download 0.266 a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17
View Download 0.251 a.45.1 Glutathione S-transferase (GST), C-terminal domain

Predicted Domain #4
Region A:
Residues: [544-672]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSEIILLKEK RAILSFLQLW EPFKSDYSQF LPIATRIAND HPYAQRVFSL TCAPQFFSYI  60
   61 NGYQIYLQQT NPATGSIPLK PIQEETFGAF QSNLHLSDSW EDFQKNFIIY LKKKGYLAIS 120
  121 DFLLSTLNR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.594 a.25.1 Ferritin-like
View Download 0.550 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.527 a.79.1 Antitermination factor NusB
View Download 0.489 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.478 a.25.1 Ferritin-like
View Download 0.313 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.299 c.26.2 Adenine nucleotide alpha hydrolases-like
View Download 0.288 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.270 d.228.1 Replication modulator SeqA, C-terminal DNA-binding domain
View Download 0.269 a.79.1 Antitermination factor NusB
View Download 0.235 a.1.1 Globin-like
View Download 0.200 a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle