YRC Public Data Repository - Protein Structure Prediction

Protein:	met6
Organism:	Schizosaccharomyces pombe
Length:	489 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for met6.

Description	E-value	Query Range	Subject Range
gi\|39951653, gi\|... - gi\|39951653\|ref\|XP_363543.1\| hypothetical protein MGG_01469 [Magnaporthe grisea 70-15], gb\|EAA55818....	278.0	[0..1]	[489..1]
MET2_EMENI - Homoserine O-acetyltransferase OS=Emericella nidulans GN=metE PE=3 SV=1 MET2_EMENI - Homoserine O-acetyltransferase OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NR...	268.0	[0..6]	[489..2]
gi\|85108758 - gi\|85108758\|ref\|XP_962641.1\| HOMOSERINE O-ACETYLTRANSFERASE (HOMOSERINE O-TRANS-ACETYLASE) [Neurospo... gi\|15982697, gi\|... - gi\|32413615\|ref\|XP_327287.1\| HOMOSERINE O-ACETYLTRANSFERASE (HOMOSERINE O-TRANS-ACETYLASE) [Neurospo...	267.0	[0..11]	[489..4]
gi\|169777279 - gi\|169777279\|ref\|XP_001823105.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83771842 - gi\|83771842\|dbj\|BAE61972.1\| unnamed protein product [Aspergillus oryzae]	262.0	[0..19]	[489..17]
gi\|88179880, gi\|... - gi\|88179880\|gb\|EAQ87348.1\| hypothetical protein CHGG_03967 [Chaetomium globosum CBS 148.51], gi\|1161...	260.0	[0..19]	[489..19]
gi\|66851549, gi\|... - gi\|70998382\|ref\|XP_753913.1\| homoserine O-acetyltransferase [Aspergillus fumigatus Af293], gi\|668515... gi\|159126353 - gi\|159126353\|gb\|EDP51469.1\| homoserine O-acetyltransferase, putative [Aspergillus fumigatus A1163]	260.0	[0..18]	[489..16]
gi\|46122561, gi\|... - gi\|46122561\|ref\|XP_385834.1\| hypothetical protein FG05658.1 [Gibberella zeae PH-1], gi\|42552386\|gb\|E...	259.0	[0..16]	[489..33]
gi\|115437998, gi... - gi\|115437998\|ref\|XP_001217953.1\| homoserine O-acetyltransferase [Aspergillus terreus NIH2624], gi\|11...	258.0	[0..19]	[489..34]
MET2_YEAST - Homoserine O-acetyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET2 PE=1... MET2 - L-homoserine-O-acetyltransferase, catalyzes the conversion of homoserine to O-acetyl homoserine whic...	252.0	[0..22]	[489..21]
gi\|31074369 - gi\|31074369\|gb\|AAP41920.1\| homoserine O-acetyltransferase [Saccharomyces bayanus]	248.0	[0..22]	[489..21]

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Predicted Domain #1

Region A:
Residues: [1-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESQSPIESI VFTDSCHPSQ QENKFVQLIS DQKIAIVPKF TLECGDILYD VPVAFKTWGT  60
   61 LNKEGNNCLL LCHALSGSAD AGDWWGPLLG PGRAFDPSHF FIVCLNSLGS PYGSASPVTW 120
  121 NAETHSVYGP EFPLATIRDD VNIHKLILQR LGVKQIAMAV GGSMGGMLVL EWAFDKEFVR 180
  181 SIVPISTSLR HSAWCISWSE AQRQSIYSDP KFNDGYYGID DQPVSGLGAA RMSALLTYRS 240
  241 KCSFERRFAR TVPDASRHPY PDRL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.0
Match:	2b61A
Description:	Crystal Structure of Homoserine Transacetylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.541803897301601	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [265-376]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTPLTPSNAH WVVHNEGNRN RRERPCRSNG SSPTSESALN SPASSVSSLP SLGASQTTDS  60
   61 SSLNQSSLLR RPANTYFSAQ SYLRYQAKKF VSRFDANCYI SITKKLDTHD IT

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.48
Match:	2b61A
Description:	Crystal Structure of Homoserine Transacetylase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [377-489]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGRGSDSPKE VMKDLSLPVL VLGIESDGLF TFDEQVEIAK SFPNATLEKI ISAEGHDGFL  60
   61 LEFTQVNSHI QKFQKEHLID IMSQTNSFER LDSQVNDTNR ESVFGEMEDI TSW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.69897
Match:	2og1A
Description:	No description for 2og1A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: