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View Structure Prediction Details

Protein: mei2
Organism: Schizosaccharomyces pombe
Length: 750 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mei2.

Description E-value Query
Range
Subject
Range
gi|73976775 - gi|73976775|ref|XP_539581.2| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
284.0 [0..70] [664..60]
gi|48734702 - gi|48734702|gb|AAH71591.1| PABPC4 protein [Homo sapiens]
283.0 [0..70] [664..60]
gi|55959639, gi|... - gi|66267552|gb|AAH94755.1| PABPC4 protein [Homo sapiens], gi|55962217|emb|CAI12298.1| poly(A) bindin...
gi|114555673 - gi|114555673|ref|XP_001170937.1| PREDICTED: poly A binding protein, cytoplasmic 4 isoform 1 [Pan tro...
283.0 [0..70] [664..60]
gi|76689279 - gi|76689279|ref|XP_881322.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
282.0 [0..70] [664..60]
gi|149023879, gi... - gi|149023879|gb|EDL80376.1| rCG31475, isoform CRA_b [Rattus norvegicus], gi|109477183|ref|XP_0010546...
281.0 [0..70] [664..60]
gi|13096978 - gi|13096978|gb|AAH03283.1| Poly(A) binding protein, cytoplasmic 4 [Mus musculus]
278.0 [0..70] [679..60]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIMETESPLS ITSPSPSDST FQVDMEKTMH ALPSSLLDSP LLSTNEHYPP KSTLLLSGPS  60
   61 PIRNIQLSAT KSSESNSIDY LTDTQNIFPN FVNNEN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.346 b.43.3 Translation proteins
View Download 0.323 d.95.2 Homing endonucleases
View Download 0.314 d.129.6 Description not found.
View Download 0.294 d.95.2 Homing endonucleases
View Download 0.250 a.4.5 "Winged helix" DNA-binding domain
View Download 0.238 d.95.2 Homing endonucleases
View Download 0.229 d.68.7 R3H domain

Predicted Domain #2
Region A:
Residues: [97-180]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYQFSTAPLN PIDACRVGER KVFTTGNVLL SADRQPLSTW QQNISVLSES PPQNGIQSYI  60
   61 SSSEQAAQAL TRKPSVTGFR SSSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.154902
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [181-369]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSNSDDIDIF SHASRYLFVT NLPRIVPYAT LLELFSKLGD VKGIDTSSLS TDGICIVAFF  60
   61 DIRQAIQAAK SLRSQRFFND RLLYFQFCQR SSIQKMINQG ATIQFLDDNE GQLLLNMQGG 120
  121 SVLSILQLQS ILQTFGPLLI MKPLRSQNVS QIICEFYDTR DASFALDELD GRIIHNCCLQ 180
  181 VAYYDAMAD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.09691
Match: 2dhsA
Description: No description for 2dhsA was found.

Predicted Domain #4
Region A:
Residues: [370-603]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVSTSSASSL SVPRGFSGML NNNSEWNNSM TMSSNQETPT AASCAVSRIG SSYGMSNNFG  60
   61 SVPLGRTESS PAWGTSGYYD VSSTSPVAPS DRNPSRQYNS IRYGLDVNPI APPNSSRLKQ 120
  121 RNSDLLNGIN PQWSPFSSNT GKVFDSPTGS LGMRRSLTVG ANASCSNPTN LSFASLTLHD 180
  181 SKADSTLSAS SLNPDLNLQR YTPTVEKHAS DRNSVDYAQI ASGIDTRTTV MIKN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [604-750]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPNKFTQQML RDYIDVTNKG TYDFLYLRID FVNKCNVGYA FINFIEPQSI ITFGKARVGT  60
   61 QWNVFHSEKI CDISYANIQG KDRLIEKFRN SCVMDENPAY RPKIFVSHGP NRGMEEPFPA 120
  121 PNNARRKLRS IASAQQIGLF PPTASKC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.30103
Match: 1d8zA
Description: Hu antigen C (Huc)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle