YRC Public Data Repository - Protein Structure Prediction

Protein:	fur4
Organism:	Schizosaccharomyces pombe
Length:	581 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fur4.

Description	E-value	Query Range	Subject Range
gi\|11278826, gi\|... - gi\|1420854\|emb\|CAA67256.1\| uracil permease [Schizosaccharomyces pombe], pir\|\|T43295 uracil transport...	322.0	[0..1]	[580..1]
gi\|145019234, gi... - gi\|39945764\|ref\|XP_362419.1\| hypothetical protein MGG_08002 [Magnaporthe grisea 70-15], gb\|EAA57033....	286.0	[0..15]	[578..4]
gi\|42552670, gi\|... - gi\|46121799\|ref\|XP_385453.1\| hypothetical protein FG05277.1 [Gibberella zeae PH-1], gi\|42552670\|gb\|E...	281.0	[0..13]	[560..1]
YEME_SCHPO - Uncharacterized permease C29B12.14c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC29... SPAC29B12.14c - purine transporter	278.0	[0..15]	[565..13]
gi\|85108010 - gi\|85108010\|ref\|XP_962492.1\| uracil permease [Neurospora crassa OR74A] gi\|28924099, gi\|... - gi\|32414281\|ref\|XP_327620.1\| hypothetical protein [Neurospora crassa], gi\|28924099\|gb\|EAA33256.1\| ur...	265.0	[0..17]	[560..6]
gi\|159131446 - gi\|159131446\|gb\|EDP56559.1\| uridine permease Fui1, putative [Aspergillus fumigatus A1163] gi\|70995872, gi\|... - gi\|70995872\|ref\|XP_752691.1\| uridine permease Fui1 [Aspergillus fumigatus Af293], gi\|66850326\|gb\|EAL...	260.0	[0..18]	[551..3]
gi\|115491959, gi... - gi\|115491959\|ref\|XP_001210607.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	254.0	[0..17]	[565..2]
gi\|116194816, gi... - gi\|88179919\|gb\|EAQ87387.1\| hypothetical protein CHGG_04006 [Chaetomium globosum CBS 148.51], gi\|1161...	246.0	[0..13]	[532..2]
gi\|190408808 - gi\|190408808\|gb\|EDV12073.1\| uracil permease [Saccharomyces cerevisiae RM11-1a] gi\|207347785 - gi\|207347785\|gb\|EDZ73852.1\| YBR021Wp-like protein [Saccharomyces cerevisiae AWRI1631] FUR4 - Uracil permease, localized to the plasma membrane; expression is tightly regulated by uracil levels ... gi\|151946414 - gi\|151946414\|gb\|EDN64636.1\| uracil permease [Saccharomyces cerevisiae YJM789] FUR4_YEAST - Uracil permease OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FUR4 PE=3 SV=2	246.0	[0..2]	[522..50]

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Predicted Domain #1

Region A:
Residues: [1-481]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESVDNNSFF SRIRNSNAYR KVKDFVILDH RPGMTMAERM LTNKDLYPVP PSKRLWGPWN  60
   61 FISFWLADAV NINTWMISAT AIELGLNWWE AWICVWVGYL ICGILVATTG RPGAVYHISF 120
  121 PVLSRSSFGT WGSLWPILNR SVLACVWYGV QAWIGGECVV LMIRSIWPSF SHIPNTMAKS 180
  181 GTETYQWVGF FIFWLLSNIA IWFPVHQIRH LFTFKAIVAP PAAIAFLIWA LVKAHGAGPV 240
  241 IHEPTKLGQY EHAWVVINGI VTCIDGFATL IVNNPDFARF ATTPGAVHWP QIITVPLAFG 300
  301 VTSLIGVLVS SASKAIYGTT LWDPTQLLAS FLDHSNAHGV RAGVFFIAFG LCIAQLGVNI 360
  361 AANSVSAGND LSALLPTVIN VRRGGYIASI IALCMCPWNL LSSNNNFTTY LSSYSVFLSS 420
  421 FAGVIIADYY FVRKGLIRVA PLYSSSSSSP YYFWKGINFR AFASYICGML INIVGMAGST 480
  481 G

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.522879
Match:	2a65A
Description:	Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [482-581]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKVPKVANTM FNLNYFLGIT VACLSHIIIC KIFPVTECGE KMLSEVPEEA DDYLLTLASE  60
   61 DSIDKDSTSE IYIDGLPTEK EVEKDDVLSI TSKKLSGCFP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits