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View Structure Prediction Details

Protein: SPAC644.05c
Organism: Schizosaccharomyces pombe
Length: 140 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC644.05c.

Description E-value Query
Range
Subject
Range
gi|114656884 - gi|114656884|ref|XP_523069.2| PREDICTED: dUTP pyrophosphatase isoform 6 [Pan troglodytes]
179.0 [0..1] [139..112]
gi|109081025 - gi|109081025|ref|XP_001113050.1| PREDICTED: dUTP pyrophosphatase isoform 5 [Macaca mulatta]
179.0 [0..1] [139..112]
gi|1071889, gi|2... - gi|70906444|ref|NP_001020420.1| deoxyuridine triphosphatase isoform 3 [Homo sapiens], gi|292877|gb|A...
177.0 [0..1] [139..1]
DUT_RAT - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Rattus norvegicus GN=Dut PE=2 SV=3
177.0 [0..2] [139..66]

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Predicted Domain #1
Region A:
Residues: [1-140]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFFVQKLSE KATIPTKGSA NSAGYDLYAA AECIVPRRGK VLVDTDLAIA VPEGTYGRVA  60
   61 PRSGLASKHS IDTGAGVIDA DYRGHVRVLL FNYSDVDFPI KVGDRIAQLI LERIVNPPVI 120
  121 LVESLEATVR GANGFGSTGV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.045757
Match: 1q5hA
Description: Human dUTP Pyrophosphatase complex with dUDP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleoside-triphosphate diphosphatase activity 5.64898078077484 bayes_pls_golite062009
dUTP diphosphatase activity 5.62861923551608 bayes_pls_golite062009
hydrolase activity 1.8120510491809 bayes_pls_golite062009
catalytic activity 1.71668532866244 bayes_pls_golite062009
pyrophosphatase activity 1.43042083356989 bayes_pls_golite062009
binding 1.21193927389015 bayes_pls_golite062009
peroxisome proliferator activated receptor binding 1.01014631701573 bayes_pls_golite062009
pyrimidine deoxyribonucleotide binding 0.378438138772693 bayes_pls_golite062009
pyrimidine nucleotide binding 0.26077271033521 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle