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View Structure Prediction Details

Protein: prp22
Organism: Schizosaccharomyces pombe
Length: 1168 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for prp22.

Description E-value Query
Range
Subject
Range
gi|39949754, gi|... - gi|39949754|ref|XP_363223.1| hypothetical protein MGG_08807 [Magnaporthe grisea 70-15], gb|EAA51285....
716.0 [0..1] [1163..1]
gi|83776192 - gi|83776192|dbj|BAE66311.1| unnamed protein product [Aspergillus oryzae]
gi|169785967 - gi|169785967|ref|XP_001827444.1| hypothetical protein [Aspergillus oryzae RIB40]
697.0 [0..1] [1162..1]
gi|159126706 - gi|159126706|gb|EDP51822.1| RNA helicase-like splicing factor (HRH1), putative [Aspergillus fumigatu...
gi|70997647, gi|... - gi|70997647|ref|XP_753563.1| RNA helicase-like splicing factor (HRH1) [Aspergillus fumigatus Af293],...
697.0 [0..1] [1162..1]
gi|46099848, gi|... - gi|71019705|ref|XP_760083.1| hypothetical protein UM03936.1 [Ustilago maydis 521], ref|XP_401551.1| ...
696.0 [0..2] [1168..7]
gi|28704113 - gi|28704113|gb|AAH47327.1| DHX8 protein [Homo sapiens]
696.0 [0..2] [1165..14]
gi|32411385, gi|... - gi|32411385|ref|XP_326173.1| hypothetical protein [Neurospora crassa], gi|28924189|gb|EAA33344.1| AT...
gi|85108466 - gi|85108466|ref|XP_962580.1| ATP-dependent RNA helicase DHX8 [Neurospora crassa OR74A]
694.0 [0..13] [1163..13]
gi|73965615 - gi|73965615|ref|XP_537627.2| PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box polypeptide 8 isoform ...
692.0 [0..2] [1165..20]
gi|114190202, gi... - gi|115401346|ref|XP_001216261.1| ATP-dependent RNA helicase DHX8 [Aspergillus terreus NIH2624], gi|1...
692.0 [0..1] [1162..1]

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Predicted Domain #1
Region A:
Residues: [1-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDLKELEYL SLVSKVASEI RNHTGIDDNT LAEFIINLHD QSKNYDEFKN NVLSCGGEFT  60
   61 DSFLQNISRL IKEIKPKDDI PTDNVNNGSN SVNGASHDLD SKDVDKQHQR KMFPGLSIPN 120
  121 STNNLRDRPA LMDNAMDELE ELSTLAKTRR NDRDSRRDER HYLNGIRERR ERSISPSFSH 180
  181 HSRTSISGQS HSSRSSRGPL LNAPTLYGIY SGVVSGIKDF GAFVTLDGFR KRTDGLVHIS 240
  241 NIQLNGRLDH PSEAVSYGQP VFVKVIRIDE SAKRISLSMK EVNQVTGEDL NPDQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.09691
Match: 1e3hA
Description: Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [295-389]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSRSTKKGSG ANAIPLSAQN SEIGHVNPLE TFTSNGRKRL TSPEIWELQQ LAASGAISAT  60
   61 DIPELNDGFN TNNAAEINPE DDEDVEIELR EEEPG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [390-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLAGQTKVSL KLSPIKVVKA PDGSLSRAAM QGQILANDRR EIRQKEAKLK SEQEMEKQDL  60
   61 SLSWQDTMSN PQDRKFAQDV RDSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.522879
Match: 1rifA
Description: Crystal structure of the UvsW helicase from Bacteriophage T4
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [474-869]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARQLTSETPS WRQATRNANI SYGKRTTLSM KEQREGLPVF KLRKQFLEAV SKNQILVLLG  60
   61 ETGSGKTTQI TQYLAEEGYT SDSKMIGCTQ PRRVAAMSVA KRVAEEVGCR VGEEVGYTIR 120
  121 FEDKTSRMTQ IKYMTDGMLQ RECLVDPLLS KYSVIILDEA HERTVATDVL FGLLKGTVLK 180
  181 RPDLKLIVTS ATLDAERFSS YFYKCPIFTI PGRSYPVEIM YTKQPEADYL DAALMTVMQI 240
  241 HLSEGPGDIL VFLTGQEEID TSCEILYERS KMLGDSIPEL VILPVYSALP SEIQSRIFEP 300
  301 APPGGRKVVI ATNIAETSLT IDGIYYVVDP GFVKQSCFDP KLGMDSLIVT PISQAQARQR 360
  361 SGRAGRTGPG KCYRLYTESA YRNEMLPSPI PEIQRQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.522879
Match: 1fuuA
Description: Initiation factor 4a
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [870-962]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLSHTILMLK AMGINDLLNF DFMDPPPAQT MIAALQNLYA LSALDDEGLL TPLGRKMADF  60
   61 PMEPQLSKVL ITSVELGCSE EMLSIIAMLS VPN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.39794
Match: 1c4oA
Description: Nucleotide excision repair enzyme UvrB
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [963-1091]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IWSRPREKQQ EADRQRAQFA NPESDHLTLL NVYTTWKMNR CSDNWCYEHY IQARGMRRAE  60
   61 DVRKQLIRLM DRYRHPVVSC GRKRELILRA LCSGYFTNVA KRDSHEGCYK TIVENAPVYM 120
  121 HPSGVLFGK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.840 a.73.1 Retrovirus capsid protein, N-terminal core domain

Predicted Domain #7
Region A:
Residues: [1092-1168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAEWVIYHEL IQTSKEYMHT VSTVNPKWLV EVAPTFFKFA NANQVSKTKK NLKVLPLYNR  60
   61 FEKPDEWRIS KQRKGGR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.839 N/A N/A a.8.9 Description not found.


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