YRC Public Data Repository - Protein Structure Prediction

Protein:	dak2
Organism:	Schizosaccharomyces pombe
Length:	591 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dak2.

Description	E-value	Query Range	Subject Range
gi\|11281433, gi\|... - gi\|3493578\|gb\|AAC78808.1\| dihydroxyacetone kinase [Schizosaccharomyces pombe], gi\|11281433\|pir\|\|T437...	704.0	[0..1]	[591..1]
DAK_PICAN - Dihydroxyacetone kinase OS=Pichia angusta GN=DAK PE=3 SV=1 DAK_PICAN - Dihydroxyacetone kinase OS=Pichia angusta GN=DAK PE=3 SV=1	675.0	[0..1]	[588..1]
DAK2 - Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress a... DAK2_YEAST - Dihydroxyacetone kinase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DAK2 PE=3 SV=1	666.0	[0..1]	[588..1]
gi\|238032869, gi... - gi\|254571923\|ref\|XP_002493071.1\| Dihydroxyacetone kinase, required for detoxification of dihydroxyac... DAK_PICPA - Dihydroxyacetone kinase OS=Komagataella pastoris GN=DAK PE=3 SV=1 jgi\|Picpa1\|39132... - null	652.0	[0..1]	[588..1]
gi\|44983723 - gi\|44983723\|gb\|AAS52822.1\| AER139Cp [Ashbya gossypii ATCC 10895] gi\|44983723, gi\|... - gi\|45190744\|ref\|NP_984998.1\| AER139Cp [Ashbya gossypii ATCC 10895], gi\|44983723\|gb\|AAS52822.1\| AER13...	633.0	[0..1]	[590..1]
gi\|110674290, gi... - gi\|110799643\|ref\|YP_694559.1\| dihydroxyacetone kinase family protein [Clostridium perfringens ATCC 1...	632.0	[0..3]	[585..1]
gi\|18309082, gi\|... - gi\|18309082\|ref\|NP_561016.1\| dihydroxyacetone kinase [Clostridium perfringens str. 13], gi\|18143757\|...	630.0	[0..3]	[585..1]
DAK1_SCHPO - Dihydroxyacetone kinase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dak1 PE=3 SV=1 dak1 - dihydroxyacetone kinase Dak1	619.0	[0..4]	[587..3]

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Predicted Domain #1

Region A:
Residues: [1-591]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVKQFVSDG HIVRPYLLGL ARSNPGLTVI EHDRVIYRTA SAPGSGDLPK VTLVSGGGSG  60
   61 HEPTHAGFVG DGALDAVACG DIFASPSTKQ IYSALKAVAS PKGTLIIVKN YTGDIIHFGL 120
  121 AAERAKAAGM NVELVAVGDD VSVGKKRGAL VGRRGLGATV LVHKIAGSAA ALGLDLHQVA 180
  181 QVAQSVIDNA ATIAASLDHC AVPGRKFETN LGPDEYEIGM GIHNEPGTFK SSPLPSIPEL 240
  241 VTEMLSILFG EKNPDNSFVE FSSKDDVILL VNNMGGMSNL ELGYATEVVS EQLAKRGIIP 300
  301 KRTMSGTFVT ALNGPGFGIT LVNASKATPD IFKYFDLPTT ASGWNVSYHN AKDWEVLADG 360
  361 KVPTAPALEH TRNEKHSGVK ADPKMFTKIL KAAVDAINEF EPKTTWYDTI AGDGDCGTTL 420
  421 VNGGEAITKA INDKSIRLDD GVNGIDDLAY IVEDSMGGTS GGLYSIYLSA LAKGVHESGD 480
  481 SELSVHTFAF ASKYALDALF KYTRARKGFR TLIDAIQPFV ETLNEGKGLD AAAKAATEGS 540
  541 EQTRKMDAVV GRASYVAKEE LHKLDSEGGL PDPGAFALAA ILNAIVEASE H

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	138.0
Match:	1un8A
Description:	Crystal structure of the dihydroxyacetone kinase of C. freundii (native form)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glycerone kinase activity	3.66907507772019	bayes_pls_golite062009
binding	0.69038000262198	bayes_pls_golite062009
catalytic activity	0.142389024724964	bayes_pls_golite062009
protein binding	0.133716715271428	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: