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View Structure Prediction Details

Protein: sec28
Organism: Schizosaccharomyces pombe
Length: 288 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sec28.

Description E-value Query
Range
Subject
Range
gi|71675440, gi|... - gi|71675440|ref|ZP_00673185.1| TPR repeat:Sel1-like repeat [Trichodesmium erythraeum IMS101], gi|716...
196.0 [0..6] [287..991]
gi|56967372, gi|... - gi|62821820|ref|NP_001017359.1| O-linked N-acetylglucosamine transferase isoform 1 [Danio rerio], gi...
178.0 [0..2] [287..116]
gi|91079875 - gi|91079875|ref|XP_967579.1| PREDICTED: similar to CG10392-PB, isoform B [Tribolium castaneum]
177.0 [0..4] [287..255]
gi|76659271 - gi|76659271|ref|XP_884992.1| PREDICTED: similar to O-linked GlcNAc transferase isoform 1 isoform 7 [...
174.0 [0..2] [287..116]
gi|66793439, gi|... - gi|66793439|ref|NP_001019747.1| UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase [Xe...
174.0 [0..2] [287..106]
gi|74007684 - gi|74007684|ref|XP_858918.1| PREDICTED: similar to O-linked GlcNAc transferase isoform 1 isoform 11 ...
173.0 [0..2] [287..116]

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Predicted Domain #1
Region A:
Residues: [1-288]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSWEASLSN ELYFVRQYFY SGNYTKLFEI DTTSMSEKGL ELTEIYMARA KLALGESLES  60
   61 IQSILTQKTP GSAAILALAG EGNMELIIDQ HGNSDSVVQT LGAIFQIKNG SFDDAMDLLK 120
  121 KSVENLEAVA LQVYIHLREH KIEAAEQTLK QALDWADEEI VLQLAQSWIK IVSGGVESYN 180
  181 DAFYVFEELN GTDSNPMTLT GMACADICLL RPEEALSSLK TALDSQPNYE EALSNMTTAI 240
  241 TDLGPDAPSQ AKNILSSFTN SSTLKLNDHL NEKAQEFDTF STQFLSTA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.69897
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.14253214573541 bayes_pls_golite062009
protein binding 1.83529176977066 bayes_pls_golite062009
signal sequence binding 1.13935627118933 bayes_pls_golite062009
peroxisome targeting sequence binding 0.69717675806841 bayes_pls_golite062009
syntaxin binding 0.0598606763736398 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle