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View Structure Prediction Details

Protein: cpy1
Organism: Schizosaccharomyces pombe
Length: 1002 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cpy1.

Description E-value Query
Range
Subject
Range
gi|320121 - gi|320121|pir||JC1380 carboxypeptidase C (EC 3.4.16.5) precursor - yeast (Candida albicans)
573.0 [0..501] [998..69]
CBPYA_MAGO7 - Carboxypeptidase Y homolog A OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=CPY...
573.0 [0..460] [1002..12]
gi|46125035, gi|... - gi|46125035|ref|XP_387071.1| hypothetical protein FG06895.1 [Gibberella zeae PH-1], gi|42553641|gb|E...
572.0 [0..505] [1001..49]
gi|76573758 - gi|76573758|dbj|BAE44842.1| hypothetical protein [Candida albicans]
gi|77023002, gi|... - gi|77023002|ref|XP_888945.1| hypothetical protein CaO19_1339 [Candida albicans SC5314], gi|68488972|...
571.0 [0..501] [998..69]
CBPYA_EMENI - Carboxypeptidase Y homolog A OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL...
CBPYA_EMENI - Carboxypeptidase Y homolog A OS=Emericella nidulans GN=cpyA PE=3 SV=1
571.0 [0..476] [1001..32]
gi|76786278 - gi|76786278|gb|ABA54912.1| carboxypeptidase Y [Coccidioides posadasii]
CBPYA_COCP7 - Carboxypeptidase Y homolog A OS=Coccidioides posadasii (strain C735) GN=cpyA PE=3 SV=1
561.0 [0..476] [1000..18]
gi|90307830, gi|... - gi|90307830|gb|EAS37461.1| carboxypeptidase Y precursor [Coccidioides immitis RS], gi|119196881|ref|...
561.0 [0..476] [1000..18]
CBPYA_NEUCR - Carboxypeptidase Y homolog A OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM...
gi|28917873, gi|... - gi|32403900|ref|XP_322563.1| hypothetical protein [Neurospora crassa], gi|28917873|gb|EAA27560.1| ca...
558.0 [0..483] [1001..41]

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Predicted Domain #1
Region A:
Residues: [1-253]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLMKQTFLYF LLTCVVSAQF NGYVPPEQNG GDIVVPKDFY EKFGEDFIRE QEESSAPLMN  60
   61 PVPERDEAEA PHHPKGHHEF NDDFEDDTAL EHPGFKDKLD SFLQPARDFL HTVSDRLDNI 120
  121 FDDDEDEHVR EKRPHDSADE DAPRRKHGKC KGKGKHHKGK HAKGKGKKSH PKPEDDSVFF 180
  181 DDERPKHHEF DDEDREFPAH HEPGEHMPPP PMHHKPGEHM PPPPMHHEPG EHMPPPPMHH 240
  241 EPGEHMPPPP MHH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [254-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPGEHMPPPP MHHEPGEHMP PPPMHHEPGE HMPPPPMHHE PGEHMPPPPM HHEPGEHMPP  60
   61 PPMHHEPGEH MPPPPMHHEP GEHMPPPPFK HHELEEHEGP EHHRGPEDKE HHKGPKDKEH 120
  121 HKGPKDKEHH KGPKDKEHHK GPKDKEHHKG PKDKEHHKGP KDKEHHQGPK EKHNERPEQN 180
  181 MQSSHELLVI EAFADLINS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [453-576]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPVEEIAEEF SRFLDTLGIE YYGNIPVHIQ ENAPKDSSIP PLFEFDDDLE LSDLTPEQFA  60
   61 YLEMLKAEGI DPMTAFRDQS HPAKPSNAQP ADSSRPYAVF SQEENGEHVN LKAFPDHTLR 120
  121 VKDS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [577-1002]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPESLGIDTV KQYTGYLDVE DDRHLFFWFF ESRNDPENDP VVLWLNGGPG CSSLTGLFME  60
   61 LGPSSINIET LKPEYNPHSW NSNASVIFLD QPINTGFSNG DDSVLDTVTA GKDVYAFLNL 120
  121 FFAKFPQYAH LDFHIAGESY AGHYIPQFAK EIMEHNQGAN FFVASGYEME KQYINLKSVL 180
  181 IGNGLTDPLV QYYFYGKMAC ESPYGPIMSQ EECDRITGAY DTCAKLITGC YQTGFTPVCI 240
  241 GASLYCNNAM IGPFTKTGLN IYDIREECRD QEHLCYPETG AIESYLNQEF VQEALGVEYD 300
  301 YKGCNTEVNI GFLFKGDWMR KTFRDDVTAI LEAGLPVLIY AGDADYICNY MGNEAWTDAL 360
  361 EWAGQREFYE AELKPWSPNG KEAGRGKSFK NFGYLRLYEA GHMVPFNQPE ASLEMLNSWI 420
  421 DGSLFA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 148.0
Match: 1wpxA
Description: Crystal structure of carboxypeptidase Y inhibitor complexed with the cognate proteinase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle