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View Structure Prediction Details

Protein: aah2
Organism: Schizosaccharomyces pombe
Length: 581 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for aah2.

Description E-value Query
Range
Subject
Range
gi|7766933, gi|7... - gi|7766933|pdb|1SMA|B Chain B, Crystal Structure Of A Maltogenic Amylase, gi|7766932|pdb|1SMA|A Chai...
gi|3089607 - gi|3089607|gb|AAC15072.1| maltogenic amylase [Thermus sp. IM6501]
340.0 [0..11] [493..111]
gi|62530449 - gi|62530449|gb|AAX85453.1| amylase [Bacillus sp. WPD616]
340.0 [0..11] [493..111]
gi|22129791 - gi|22129791|gb|AAL62457.2| alpha-cyclodextrinase [Thermus sp. YBJ-1]
337.0 [0..11] [493..111]
gi|15375096 - gi|15375096|dbj|BAB63955.1| alpha-cyclodextrinase [Geobacillus stearothermophilus]
337.0 [0..11] [493..111]
gi|56419238, gi|... - gi|56419238|ref|YP_146556.1| alpha-cyclodextrinase [Geobacillus kaustophilus HTA426], gi|56379080|db...
337.0 [0..11] [493..111]
gi|6561863 - gi|6561863|gb|AAF17100.1|AF208224_1 alpha-amylase [Emericella nidulans]
gi|49092156, gi|... - gi|67525889|ref|XP_661006.1| hypothetical protein AN3402.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
332.0 [0..22] [505..16]

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Predicted Domain #1
Region A:
Residues: [1-497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNYRRNICLR IGWMLLFAFI PAYAGHSAEE WKRRSIYQII TDRFSLEEGA TERIPCDPVR  60
   61 FMYCGGTWNG IRNHLDYIQG MGFDAIWISP IFENVEGNDI DGSSYHGYWT TNLYELNHHF 120
  121 GTKEEFMELI QELHKRDIWI LLDVAINSMA INGPLEQMSF EKVIPFNDAS FFHPHCWVDY 180
  181 ESNDIESVQN CWLGDENLLL ADVDTENEVV LSVLEKWIKN VVQEYDIDGI RFDAIKHAPI 240
  241 EFWLRMSKAA DIFTIGEYFT GSPAEACDYQ NSGLDSFLNF PLYWPITWAF NNTGLQCEAL 300
  301 AIAINQINEE CNDINVLGTF IGNHDLPRIS HNNTDQARIM NAITFVMMWD GIPIIYYGTE 360
  361 QNFNSYHDPF NREALWLSNF DMENVYYKLI GILNRFRKSV QRQEENYVNT RSTILSVKIH 420
  421 HIVVQKLNVI TVLNNYGIHN EERLSIVFKP LGASPKDTFF DIINNQKYVV NTDGTLKVVI 480
  481 TNGFPIVLYP TSKIETS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 89.69897
Match: 2guyA
Description: No description for 2guyA was found.

Predicted functions:

Term Confidence Notes
hydrolase activity, acting on glycosyl bonds 5.36248919165223 bayes_pls_golite062009
glucan 1,3-beta-glucosidase activity 4.9497656520055 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 4.55801959095491 bayes_pls_golite062009
hydrolase activity 4.05312354194822 bayes_pls_golite062009
chitinase activity 4.02601525947212 bayes_pls_golite062009
glucosidase activity 3.48584664974971 bayes_pls_golite062009
beta-glucosidase activity 2.93854518942359 bayes_pls_golite062009
alpha-amylase activity 2.09193270404736 bayes_pls_golite062009
amylase activity 2.03484942782894 bayes_pls_golite062009
catalytic activity 1.85569074294201 bayes_pls_golite062009
transporter activity 1.28975867300692 bayes_pls_golite062009
binding 1.08189849662259 bayes_pls_golite062009
transmembrane transporter activity 1.06875155491269 bayes_pls_golite062009
hyalurononglucosaminidase activity 0.799539531748231 bayes_pls_golite062009
substrate-specific transporter activity 0.798668027833638 bayes_pls_golite062009
hexosaminidase activity 0.763360027922833 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.543615761700598 bayes_pls_golite062009
alpha-glucosidase activity 0.502835520523619 bayes_pls_golite062009
alpha-1,3-glucan synthase activity 0.434118980237671 bayes_pls_golite062009
beta-N-acetylhexosaminidase activity 0.369121784919131 bayes_pls_golite062009
carbohydrate binding 0.28185708488534 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.266938437560648 bayes_pls_golite062009
active transmembrane transporter activity 0.247544462005515 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [498-581]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPQFTATLLP EITFVPSITV TTHYVLPTLL APLGYDIREH PGGQQFWNTL TAKSEAKTIR  60
   61 SFTKLKLFIL LIAVPFALPM IILI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle