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View Structure Prediction Details

Protein: pen-PA
Organism: Drosophila melanogaster
Length: 737 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pen-PA.

Description E-value Query
Range
Subject
Range
PUM1_XENLA - Pumilio homolog 1 OS=Xenopus laevis GN=pum1 PE=1 SV=1
430.0 [0..7] [482..696]

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Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSSEPKGPA NVANTASPLK AHESSGKRAN GQKFKPGGAG GARKFDKFGG GAGKSFVKPG  60
   61 AGGAKKFDKS GPGGFKKFDK SGATGDKRLG GNKFRGKPQT Q

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [102-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQAPAEGEKQ DWNKFKKEKK DLKLKRKSAK DTYEISKEAN QIHEKLRCRR TENKDKLVEQ  60
   61 IYKVLNVGDT ISKVVKAHDT ARVIQSMLKY ASPALRAEIS EKLLPFTVEM CQSKYAQFCV 120
  121 QRMLKYGAPA TKAKLVDSLY GHIVRLAGHS IGSGLLDSMY QSATPNQRIY MRQEFYGDLY 180
  181 RKAKDSNVKT LSDTYKEATN MKASILGSVK ANLDHVANKQ LVDSALVHAV MLEYLRACDE 240
  241 DEEKLEETVT AFAALVPHML STKEGSEAAV ICFYKSTPKN RRAIIKNIKE HLLKIANHEH 300
  301 GHVFLISLLN ALDDTKATKK AIYDHLHGDL KALMSSPYGR RVIQWLVAPG DTTCFHPEFI 360
  361 RTVEEGLAFG KK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 94.39794
Match: 1ib2A
Description: Pumilio 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.72866289380549 bayes_pls_golite062009
protein binding 1.50424196360192 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [474-631]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKELRRKEIL EQIEAPIAQS IAEDAAFWLS NSHIGLVTGD ILNHIQGESY EKAASALAQV  60
   61 VVQPEWRISA DAAGPQPQDK KKPHNDVEAI IAQATKQRRK LLYVESSSDD EDEDEDEDEE 120
  121 SDDEGDEKEQ KEAAADDAEP KVKKAKKEPK KPKAKEEE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [632-737]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAAPLVSGIE EAGMHIVLKK ILKNDGKREG TPFSQQLLQN LSSDVLKAWL GVNRACFVLL  60
   61 KLVEECPALL DDCKKAIAAE RSLSQILADR KTPGAKLLAA KLDIGK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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