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View Structure Prediction Details

Protein: Tak1-PA
Organism: Drosophila melanogaster
Length: 678 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Tak1-PA.

Description E-value Query
Range
Subject
Range
gi|125982149|ref... - GA14958-PA [Drosophila pseudoobscura], GA14958 [Drosophila pseudoobscura pseudoobscura]
gi|125982149, gi... - gi|54643349|gb|EAL32093.1| GA14958 [Drosophila pseudoobscura pseudoobscura], gi|125982149|ref|XP_001...
331.0 [0..1] [678..1]

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Predicted Domain #1
Region A:
Residues: [1-339]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATASLDALQ AAYVDFSEIT LREKVGHGSY GVVCKAVWRD KLVAVKEFFA SAEQKDIEKE  60
   61 VKQLSRVKHP NIIALHGISS YQQATYLIME FAEGGSLHNF LHGKVKPAYS LAHAMSWARQ 120
  121 CAEGLAYLHA MTPKPLIHRD VKPLNLLLTN KGRNLKICDF GTVADKSTMM TNNRGSAAWM 180
  181 APEVFEGSKY TEKCDIFSWA IVLWEVLSRK QPFKGIDNAY TIQWKIYKGE RPPLLTTCPK 240
  241 RIEDLMTACW KTVPEDRPSM QYIVGVMHEI VKDYTGADKA LEYTFVNQQI VTKESDGTVA 300
  301 AQPDSLSSQE GELSPSSTQL TPTTAANANV NAIAISKTT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.522879
Match: 2evaA
Description: No description for 2evaA was found.

Predicted Domain #2
Region A:
Residues: [340-478]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSSMTENTSS TSSDITPTNS GQLDNNPLFY MVTNRWDAIP EEESNESRND SFNLTSSAEA  60
   61 TQRLETIRNG MILMACKPME QLTLDVEANG FDLSPSESSS SSTNAKSDGR ERLTVTDTKP 120
  121 VMMTTDLSNN NGGIHAHSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [479-678]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLLSHANGWQ ARDEELQEQE HEQEIVNSLD VDVDPDEDEN DGTEQSLAEI LDPELQPEPP  60
   61 IPNDAESQLI YRDHRHMAKE YLSVDTNLYY AQDFKDKLIV QMDRTEREQK QELLRKMKDK 120
  121 EGLQSLYNNL QQQYASRQLA AGHHPQPHPH PHPNQLQHPH SHPPMHFLQD EGCGLLPGSV 180
  181 CGGSESVEEG WVVIPPHHNA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1k04A
Description: FAT domain of focal adhesion kinase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle