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View Structure Prediction Details

Protein: gi|22832669, gi|...
Organism: Drosophila melanogaster
Length: 1240 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|22832669, gi|....

Description E-value Query
Range
Subject
Range
gi|114685508, gi... - gi|114685510|ref|XP_001171406.1| PREDICTED: RUN and TBC1 domain containing 2 isoform 2 [Pan troglody...
1005.0 [0..89] [1240..3]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHHHPLPIA TATASAFAFA FATQLHPSRT WHGDNAVGVP DGEHFVVATE QQCHTVHSCP  60
   61 AYKSTYASSS PSAPSIMKQA QWAAAIS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [88-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAVGNGSDYK ERLIASVKKE VKQLMEEAVT KKYVHEESSS VTSLCGAVEA CLSQGLRRRA  60
   61 LGLFKTSSTT ALLHKIAKSC PEAEHISKLV QEIEASDPSK RSSSSSDSFQ RPPMLKKSSS 120
  121 NSMSTGTNAA ASTSSASASI SVSASTSSMS LASMKYLWIR LALYEKRLTK IIEYLVSNAS 180
  181 SFYDRDSLVA DSDYGSILSS LLVGPCALEF TRAKTADHYW TDPHADELVQ RHRISSCRRS 240
  241 SSTCSRPAII NFKRSLNTSS DEAG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.87
Match: 2cxfA
Description: Crystal structure of the RUN domain of mouse Rap2 interacting protein x
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [352-575]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGSFKSIASA SVAKDYVESL HQNAKATLLY GKNNVQVLPK DVAEPMPGYL SLHQHIQTLT  60
   61 IKWTPNQLMN GYTEAEEAED IDKDAFWAYA LNINVDEIVY VHCHQSRGED SGGTVILVGQ 120
  121 DGVQRPPIHF PEGGHMQQFL SCLETGLLPH GQLDPPLWSQ RGIGKMFLWP RSMRRRILPS 180
  181 VMESVDETPI DYVFRIVSKS RHEEFAATHS ILDFVRSTPR RAQL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [576-646]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSCSTTGSSD CSNKSLSIDQ FPMESPLILQ QQQQQQQQLL QAQSTSIEMV CSTMRRQIIS  60
   61 RAFYGWLAYC R

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [647-788]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HLSTVRTHLS GLVHGRITPE MKADEEGLTK ERWQLLNVNG VLENATEFYR LVYFGGVQPE  60
   61 LRQEVWPYLL GHYAFGSTTE DRKKQDETCK HYYETTMSEW LAVDAIVQQR EKEKTARAVA 120
  121 KLSSGSNSGN DRTVRAADLE AG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [789-915]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDLENEVFED ISDISDPGDL EFDEQQQQQQ QQAECAVSGN HLTVKPIPRA MKTSTDSGHV  60
   61 DESFNELDEP DEEDNKQKQQ QDEKISESES KLPDYRKLEE QINQEPSCSA STASSYETVG 120
  121 PGEVHQR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [916-1240]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNSDTRSVLS PEYLSADDLQ LPDDEDAVRP PPPPAAAAVI ITKASVDITN WERSPKAAEG  60
   61 DQMSPLEEQA GESGGAGVNM DALQQPKSAC ASPASSNGGV YSSELLEQFG LNLHRIEKDV 120
  121 QRCDRNYWYF ANENLDKLRN VISTYVWEHL DVGYMQGMCD LVAPLLVIFD DESLSYSCFC 180
  181 KLMERMIENF PSGGAMDMHF ANMRSLIQIL DSEMYDLMDS NGDYTHFYFC YRWFLLDFKR 240
  241 ELVYDDVFAT WEVIWAAKHI ASGHFVLFLA LALLETYRDI ILSNSMDFTD VIKFFNEMAE 300
  301 RHNAQSVLQL ARSLVLQLQM IIENK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.522879
Match: 2qfzA
Description: No description for 2qfzA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle