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View Structure Prediction Details

Protein: CG1695-PB
Organism: Drosophila melanogaster
Length: 1148 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG1695-PB.

Description E-value Query
Range
Subject
Range
gi|73995364 - gi|73995364|ref|XP_543450.2| PREDICTED: similar to RUN and TBC1 domain containing 2 [Canis familiari...
1191.0 [0..1] [1147..44]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEAVTKKYV HEESSSVTSL CGAVEACLSH GLRRRALGLF KTSSTTALIQ KIAKICPEAD  60
   61 YVSRRLLELE LAQESHAVSG KRSSCSSDSI IKPKLLSK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.9
Match: 2cxfA
Description: Crystal structure of the RUN domain of mouse Rap2 interacting protein x
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [99-226]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSGSSNSVTT INTVTNGAGA GPGGGGGASA PLGKYLWIRL ALHEKRLAKI IEHLVSNANS  60
   61 YYDREALVAD PDYGSILSSL LVGPCALEFT RAKTADHYWS DPCADELVQR HRISSGNRTP 120
  121 PTTHRPII

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 2dwgA
Description: No description for 2dwgA was found.

Predicted Domain #3
Region A:
Residues: [227-451]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFKRSLHTSS EDTSSGSFKA CSPASVAKDY VESLHQNSRT TLLYGKNNVL VLPKDVSEPM  60
   61 PGYLSLHQSI QSLTIKWTPN QLMNGYNDGD GGDKSFYWSY ALNINVDEIV YVHCHQNRGG 120
  121 DTGGTIILVG QDGVQRPPIH FPEGGHLQAF LSCLETGLLP HGQLDPPLWS QRGIGKLFPW 180
  181 PKSVRRHILP SVMEAGGSVT DETPIDYVFR VVSKCQHEEF LASHP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [452-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILELGRSSPR RKHLGSCSTT GSSDCSSKSL SIDQSSCETP LIQASQSTSI ELVCSTMRRQ  60
   61 IISRAFYGWL AYCRHLSTVR TH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [534-843]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSGLVNGRIM PDLAADEEGL TRGKWLAMHE DGVVTGDLEL YRLVYFGGVE PELRKEVWPY  60
   61 LLGHYDFGST PEERKKQDET CKHYYETTMS EWLAVEAIVR QREKEKTALA VAKLSAEQAR 120
  121 LAANATSSSN PHQKLANGSQ QLQLEHGNGE EDQENLVLDE GENDVFDDND FSDISDPGDL 180
  181 FDEPELGQEA EEQEQSNLEE EVFEKQEDEE DQEDHDQREM PRLSEKLVLE FQNIDNMEPL 240
  241 RLQENCFADS ETENDLGLGL DSSGNILMLS IKSSPSTSSY ETVGNEFLDM AEAKLEEEEP 300
  301 PGQLSKFHSA 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.51
Match: 2qq8A
Description: No description for 2qq8A was found.

Predicted Domain #6
Region A:
Residues: [844-1148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDVRLDNQDE EESSQPATAV IITEAASLDA LDDDPTEEFT SRKTSLMSPL NEDITVVASL  60
   61 DALQEPKSAC VSPASSNGGV YSVELLEQFG LNLHRIEKDV QRCDRNYWYF ANENLDKLRN 120
  121 VISTYVWEHL DVGYMQGMCD LVAPLLVIFD DESLSYSCFC KLMERMIENF PSGGAMDMHF 180
  181 ANMRSLIQIL DSEMYDLMDS NGDYTHFYFC YRWFLLDFKR ELVYDDVFAT WEVIWAAKHI 240
  241 ASGHFVLFLA LALLETYRDI ILSNSMDFTD VIKFFNEMAE RHNAQSILQL SRSLVLQLQT 300
  301 IIENK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.221849
Match: 2qfzA
Description: No description for 2qfzA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle