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View Structure Prediction Details

Protein: CG6227-PA
Organism: Drosophila melanogaster
Length: 1224 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG6227-PA.

Description E-value Query
Range
Subject
Range
gi|50755152 - gi|50755152|ref|XP_414629.1| PREDICTED: similar to Prp5-like DEAD-box protein [Gallus gallus]
573.0 [0..259] [1213..106]

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Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSSGRDRD RERDRERERE RDRERERDRD RERDNRHDSR SRDYDMGKSR NGGGGGAGGG  60
   61 SRNMREDRKR GKDMISDRGK RDDKRRKCSR SKD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [94-216]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YEKDNSPHYR RLDKDRDRDR DRDRQREKER EREKEKEREK EKERERDKDR ERDRQREKES  60
   61 DSRRAAAAAP LIIPLLSTSC SEEEVEEIDK EEQQRRLEQE MIKRRERIER WRAERKRDTK 120
  121 AAV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [217-458]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VAPSLVNSAK KWSLEDESEE DDSNPAPPLD SGKKDAEPDS PPSKFHSIRK RFDDDVVESK  60
   61 FSPVKRPTFS KSFGKLGIGL ATKAEADIKK EPPPVDTKKE IKKKPEPVAA KMEIVEEPTV 120
  121 AAGEKTKKEP EQPHVGAKSE PEVEDKPQPE AEPEDEIDPL DAYMQEVNNE MRRVNNFVNP 180
  181 PAKSQGVVIL TGVAKKKTTT LKKGEVIEQN MDSLEYSSED ELEDIRDTAV NLAMKHRKEL 240
  241 AK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.45
Match: 1h1kI
Description: THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [459-509]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDHSSVTYAP FRKNFYVEVP ELTRMTAADV EKYRSDLEGI QVKGKGCPKP I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 109.0
Match: 2db3A
Description: No description for 2db3A was found.

Predicted Domain #5
Region A:
Residues: [510-713]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTWAQCGVSK KEMEVLRRLG FEKPTPIQCQ AIPAIMSGRD LIGIAKTGSG KTLAFILPMF  60
   61 RHILDQPSME DGDGAIAIIM APTRELCMQI GKDIRKFSKS LGLRPVCVYG GTGISEQIAE 120
  121 LKRGAEIIVC TPGRMIDMLA ANSGRVTNLR RVTYVVLDEA DRMFDMGFEP QVMRIIDNVR 180
  181 PDRQTVMFSA TFPRQMEALA RRIL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 9.43
Match: 2gxqA
Description: No description for 2gxqA was found.

Predicted Domain #6
Region A:
Residues: [714-941]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKPIEVIVGG RSVVCKEVEQ HVVILNDDAK FFKLLELLGI YQEAGSIIVF VDKQENADIL  60
   61 LRDLMKASYP CMSLHGGIDQ FDRDSTIIDF KSGKVRLLIA TSVAARGLDV KDLILVVNYD 120
  121 VPNHYEDYVH RCGRTGRAGK KGSAYTFITP EQSRYAGDII RAMDLSGTLI PAELQALWTE 180
  181 YKALQEAEGK TVHTGGGFSG KGFKFDEQEF NAAKESKKLQ KAALGLAD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.221849
Match: 2hjvA
Description: No description for 2hjvA was found.

Predicted Domain #7
Region A:
Residues: [942-1112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDDEEDIEQD IDQQIEQIFA AKRTVKDTSA AATAAAAAAA AAAAAAAAVS GANPALASAA  60
   61 AQAAAAAAAA NIAIAAASAP AAAGGAPSVA MGGALSSDKL ELAKRLASKI NSSKNLDTKG 120
  121 SVVTVEPMIK GPHVTGAAAT LLTARTVAEQ MAAKLNNKLN YQPKEDEEGL G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1113-1224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLVGGTTNPF TKYEEELEIN DFPQQARWKV TSKEALAQIS EYSEAGLTVR GTYVPQGKNP  60
   61 PDGERKLYLA IESCSELAVQ KAKREITRLI KEELLKLSSA HHVFNKGRYK VV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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