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View Structure Prediction Details

Protein: dah-PA
Organism: Drosophila melanogaster
Length: 649 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dah-PA.

Description E-value Query
Range
Subject
Range
gi|3127924 - gi|3127924|emb|CAA75752.1| dystrobrevin B (mDTN-B) [Mus musculus]
473.0 [0..14] [648..18]

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Predicted Domain #1
Region A:
Residues: [1-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRSSVPVQL TKLRNSAEAV ASIAREKGSQ GGQGQKQQVD KELSTIMDDL QRDYGNYKYT  60
   61 VYRCASKFVA LQKIFHTGKI PYKLVLAILD RHNLSGGLEL MVPPFQLTSL LHDVYFACEK 120
  121 LGHFNQDANY KLDRATGLLA NFFWNVYDPQ RRHSISLLEI RITFILLCKL YSSDHLVGDI 180
  181 FGLLADPKSQ IISRYAFEQL LATLSKLLSY LGEAKAYGVH NLPLAMEQCF ARCPHGVGGL 240
  241 TEPQFHKLWT GAGVQTRFLI YGNLLALVKR IEDTEHLI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 98.09691
Match: 1eg3A
Description: Dystrophin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.83442164502628 bayes_pls_golite062009
protein binding 1.49196141050291 bayes_pls_golite062009
calcium ion binding 1.21855083755727 bayes_pls_golite062009
cation binding 1.02568324480988 bayes_pls_golite062009
metal ion binding 1.02568324480988 bayes_pls_golite062009
ion binding 1.02225722854811 bayes_pls_golite062009
cytoskeletal protein binding 1.01146756530391 bayes_pls_golite062009
actin binding 0.514092416982902 bayes_pls_golite062009
structural constituent of muscle 0.235603681531933 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [279-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSNSCAGCRK EHIVGIRFRC QVCRDISLCL PCFAVGFAGG RHEPGHRMCE VFVEDQPPLR  60
   61 WTRHLARL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.0
Match: 2e5rA
Description: No description for 2e5rA was found.

Predicted Domain #3
Region A:
Residues: [347-649]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CGWLVMPRKT QEEERRGFCN AQESGPALGQ SAATPIPAET RSVRSQCQEK DRTVVLQQQQ  60
   61 QELCSLTGLA SEASSRLQSI IDRLLLQNAK LETQLQTVAT ASSSEISQFL SAHQCFLLQI 120
  121 IEDMRQLSHA SAVTSPPPAP AAQVAPSAAP LVSSTFLSSS TPQRQMLFDM YAPVGANLTH 180
  181 SINGADLNRS YLEANKSDYS LNDISLWFDQ RRSSVQPGQG PGSLPAPLPL PMPLGALLEQ 240
  241 QPANGGDGRD TEMVNFKLLL HKVKEIVEDS YSDNAELSAA TQNLENVLDS IIKSEEQQRR 300
  301 IST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.39794
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle