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View Structure Prediction Details

Protein: CG42251-PD
Organism: Drosophila melanogaster
Length: 1416 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG42251-PD.

Description E-value Query
Range
Subject
Range
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
500.0 [0..4] [997..1910]

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Predicted Domain #1
Region A:
Residues: [1-327]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLSFLFRPF FISVLPAIRT KQLPFGEAQQ ALQLQPAAAA ATAAATTSAA AAANATAAAP  60
   61 QLPPPLPVPV ATLPNQAATA AAAATAAILA THQQQQQQQH QHLSNNNNNG GSTHGQQHTH 120
  121 SNNNNTLPVG AQQQQQQQHQ QQRATLQHPP LPNSNIKQAS VKLIEGYSDP KDTRNHKKVY 180
  181 HKKAKKRSTT GHKRHQQQQQ QQQPHQQQLQ QQQQQTLPTP RSAQQQQQLQ QKLQQRHSTY 240
  241 NNNNGNSRKD KRNSQYNSDS SAPKSSDDEA DIDEEVEQQP LPVPQAPVQS ASQPAAGLNS 300
  301 PDSISDDLVR PLPPQLQRSP RKLTVAP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [328-581]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEHNKRQPSP YYYSDLLKSR DKDKDKDKDK DKDKDKDKDK DKDKDKERDK DREDFKLKCR  60
   61 QSTASEPPQQ TQTQLGGYRK SSSLDVPPAE EQPEAESHEE EDPRTGQDSQ STPKRYSFTE 120
  121 EGVHIIRCET PSTSTSEESD CSECLKRREW HARALALVRK TCNVQPRNQN PTGSELQLQL 180
  181 QHCDAGEGEL LKCCPPPPAP AENQSQVQPM PPHRLLGPAA VCGACITSAP ASSLAGGRGS 240
  241 ELGDDLEEEY FRPR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 2tmaA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [582-801]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIFYVHPHGV HECIECAQPA QPATVPAPTL SNPSLDIYGD DEDEVDGDED EDEEDDSEDI  60
   61 MGSRRRQIYE TAFDCKIAKS DDDLDEVDRI TNCSVLLQLS NGNGGDISKV TGSSKTRAEC 120
  121 KRAKNSKNQA LQEQTGEAHV QVHHVEAELG KLQLSQVDQQ NQNQNQSQNQ QHGVSATGSG 180
  181 ASASSTQQLP VRGYTPSPPS TAPLPMKFPG KHDRYLNMNS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [802-920]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRSAPNLPAA NPAHPRLRDL RLPIQSMRHQ CGGSSNDNSL TDSAYVNPPS TNSNSNAASA  60
   61 SASASVSATG SAAPRRPRSF VLESGRVLEL RRSAQGHQGG QSTHHHHHHH HHAPGSRRN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [921-1094]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RHGQSQGQTT GGGHNYSSTE SIATSSSGGS MESLRSSTSE GNRSTSSSES RHSSSLSSHS  60
   61 SESGSGGSGG SGGSSVAYPL RPAPLLLHSK LHILSPISDK SSQEPASASA SEQSQQPSQQ 120
  121 LAPMASQEDD STTSGAPAGN QVQVNASLKQ PRSNRGAPNK ALLQLADELL GSDS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1095-1175]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GISLHSREDG KPQALALQRL TLPKLQLIGA EGTTTSATAS GAGGSSATGG SSGAGGSGSG  60
   61 SVVASGSTGI QQDLRDLPFD M

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1176-1416]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKLRRRKTLQ QEAACTSGSA TSVDLGELPF DMPKLRRRLR ANQAEINNLL MHSTESSGIS  60
   61 QASSSHSMRD DQKMSSKLDT ALFRQNLTLN LNESRQATKQ FGSLDLRGLN SNKELNMNLS 120
  121 QGYVTAVDLI DVTIPLERQG WYHGAITRIE AETTLRPLSE GSFLVRNCES TKQDYSLSLK 180
  181 GAKGFMHMRI QRNETGQYIL GQFSRPFETV PEMIRHFCLN RLPVRGAEHM CLIEPVIAQL 240
  241 L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.045757
Match: 2h8hA
Description: No description for 2h8hA was found.

Predicted functions:

Term Confidence Notes
binding 0.434026084000615 bayes_pls_golite062009
protein binding 0.31534665043077 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle