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View Structure Prediction Details

Protein: HP5-PB
Organism: Drosophila melanogaster
Length: 837 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HP5-PB.

Description E-value Query
Range
Subject
Range
gi|70878483 - gi|70878483|gb|EAN91735.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71649745 - gi|71649745|ref|XP_813586.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
300.0 [0..2] [837..768]

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Predicted Domain #1
Region A:
Residues: [1-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIFDMVKAA PPPQTINPVD TKLSTPSPIP PDSPIDVNDL LESGNQLDEN DLRMSRKSKN  60
   61 VEQCSIDLFD SETSFDHLDE SLAKRKRKSV ANSKPNKSRK STVSASTPHN KRPKVSIDDD 120
  121 GEAIEEDQQS MVVVPTKTKA QQKMFSDQQS PNVKRKVRVL LRRLKQTEID SAVESLANSS 180
  181 FINVPEIVNQ SGTSGRSRHK KRKTSPKKQK SSTAQTN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [218-356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FHIKVPLQNG AKKRALNHSL RAHTPPPSLA KSSESTHSAL KRSPKPKIKA KRLSSRGRNT  60
   61 DPDLVKRYGA HFFGCVVKVR RTRLPSAKWP DCKPPPIGDG VVRKVYPKKA VSFSEAVEIL 120
  121 GSPGGPSRRS TFGSLSSRG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [357-438]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APKPTRLQRV DATGNVLEDI ALTSTPLFSS SSGGSRERVR RRSCNGTPVV GRLKLRRLGR  60
   61 LSIDNSSSRS DGGGDNDDDD EE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [439-513]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YIVPNDVPGS QRSGTPPPKK KKISFTTTIS DDEDEKPVLK KQKDAQKKQP KPLKERSNKK  60
   61 TDKMLNEKET TDKMQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [514-837]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKKEKKTENS PVVEIESSDP DVEIKPPVKE IETNEREGDA HETETNEVER DREEQFVDAT  60
   61 EKNTDEAKEK KVVKDMPELK EADNSEEKSE DAREEVLLDE DEKNLEENAA EISDNAVKSL 120
  121 EKPTNEDRVE KVEDEVEHAE EFSDLPTPPQ LPSTTDDNED DVLEIQTSLD DVRQLHTPSS 180
  181 RQSTPKSRSR LDSGDSDCSF KSASDNAKLL AGQAIEETEQ KASKAPNDDE DQQTAATIIG 240
  241 DPIDSPELPA ELMTPPSAPR TVNGEPTSES RSTATTYYSP MEDPMATLDD VIMDQLSEPN 300
  301 FQLNSSRHAI SRGTLDEIMT ALES

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle