YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: alpha-Man-I-PK, ...
Organism: Drosophila melanogaster
Length: 643 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for alpha-Man-I-PK, ....

Description E-value Query
Range
Subject
Range
gi|840752, gi|21... - gi|840752|emb|CAA57963.1| alpha 1,2 mannosidase [Drosophila melanogaster], pir||S60710 alpha 1,2 man...
746.0 [0..1] [643..1]

Back

Predicted Domain #1
Region A:
Residues: [1-125]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCPKTSKTTP LLLIGGICFV IVLVGITGIT LINNINLSNI IRLNEKVASD SVSNNENQIK  60
   61 ELNYVNNHPR NVYLKLNASS RDDEDDEQMQ KEQEQLELPK ISAVIGGSKP KVEDNQVKES 120
  121 SEVIS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [126-643]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSTSTFSMRS SAGELTSTSA PLSSIVSVTA PPMPFGGVKY NQSSGLIDYE KRNQVVKMME  60
   61 HAWHNYKLYA WGKNELRPLS QRPHSASIFG SYDLGATIVD GLDTLYIMGL EKEYREGRDW 120
  121 IERKFSLDNI SAELSVFETN IRFVGGMLTL YAFTGDPLYK EKAQHVADKL LPAFQTPTGI 180
  181 PYALVNTKTG VAKNYGWASG GSSILSEFGT LHLEFAYLSD ITGNPLYRER VQTIRQVLKE 240
  241 IEKPKGLYPN FLNPKTGKWG QLHMSLGALG DSYYEYLLKA WLQSGQTDEE AREMFDEAML 300
  301 AILDKMVRTS PGGLTYVSDL KFDRLEHKMD HLACFSGGLF ALGAATRQND YTDKYMEVGK 360
  361 GITNTCHESY IRAPTQLGPE AFRFSEAVEA RALRSQEKYY ILRPETFESY FVLWRLTHDQ 420
  421 KYRDWGWEAV LALEKHCRTA HGYCGLRNVY QQEPQKDDVQ QSFFLAETLK YLYLLFSDDS 480
  481 VLPLDEWVFN TEAHPLPIKG ANAYYRQAPV TLPVSNAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 180.0
Match: 1nxcA
Description: Structure of mouse Golgi alpha-1,2-mannosidase IA reveals the molecular basis for substrate specificity among Class I enzymes (family 47 glycosidases)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mannosyl-oligosaccharide mannosidase activity 7.089685350864 bayes_pls_golite062009
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity 6.95179264736435 bayes_pls_golite062009
mannosidase activity 5.20286438265852 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 4.31319275372149 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 3.65589746311782 bayes_pls_golite062009
hydrolase activity 2.67964748309919 bayes_pls_golite062009
binding 1.49199031708525 bayes_pls_golite062009
catalytic activity 1.31873306707813 bayes_pls_golite062009
cation binding 0.362242764130218 bayes_pls_golite062009
metal ion binding 0.362242764130218 bayes_pls_golite062009
protein binding 0.36081692928767 bayes_pls_golite062009
ion binding 0.355220167272296 bayes_pls_golite062009
calcium ion binding 0.121126738064555 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle