YRC Public Data Repository - Protein Structure Prediction

Protein:	c12.1-PA
Organism:	Drosophila melanogaster
Length:	259 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for c12.1-PA.

Description	E-value	Query Range	Subject Range
gi\|71020741, gi\|... - gi\|71020741\|ref\|XP_760601.1\| hypothetical protein UM04454.1 [Ustilago maydis 521], ref\|XP_402069.1\| ...	165.0	[0..1]	[259..62]
gi\|54643983\|gb\|E... - GA11429-PA [Drosophila pseudoobscura], GA11429 [Drosophila pseudoobscura pseudoobscura] gi\|125983804, gi... - gi\|54643983\|gb\|EAL32726.1\| GA11429 [Drosophila pseudoobscura pseudoobscura], gi\|125983804\|ref\|XP_001...	158.0	[0..1]	[259..1]
gi\|57100930 - gi\|57100930\|ref\|XP_533756.1\| PREDICTED: similar to RIKEN cDNA 0610040D20 [Canis familiaris]	136.0	[0..1]	[259..1]
ENSCJAT00000008051 - null tr\|G1SFT2\|G1SFT2... - pep:novel chromosome:oryCun2:1:121904811:121918604:1 gene:ENSOCUG00000001629 transcript:ENSOCUT00000... gi\|109108351 - gi\|109108351\|ref\|XP_001089958.1\| PREDICTED: similar to RIKEN cDNA 0610040D20 [Macaca mulatta] gi\|114639892, gi... - gi\|55636843\|ref\|XP_508705.1\| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes], gi\|1146398... CWC15_PONAB - Spliceosome-associated protein CWC15 homolog OS=Pongo abelii GN=CWC15 PE=2 SV=1 CWC15_PONPY - Protein CWC15 homolog - Pongo pygmaeus (Orangutan) CWC15 - CWC15 spliceosome-associated protein homolog (S. cerevisiae)	135.0	[0..1]	[259..1]
CWC15_MOUSE - Spliceosome-associated protein CWC15 homolog OS=Mus musculus GN=Cwc15 PE=1 SV=1	134.0	[0..1]	[259..1]
tr\|G3HSN1\|G3HSN1... - Protein CWC15-like OS=Cricetulus griseus GN=H671_4g13327 PE=4 SV=1 CWC15_RAT - Spliceosome-associated protein CWC15 homolog OS=Rattus norvegicus GN=Cwc15 PE=1 SV=1	134.0	[0..1]	[259..1]
GL50803_4883 - \| organism=Giardia_Assemblage_A_isolate_WB \| product=hypothetical protein \| location=GLCHR02:216520-... gi\|157433633, gi... - gi\|71078504\|ref\|XP_771761.1\| hypothetical protein GLP_546_74871_79250 [Giardia lamblia ATCC 50803], ... ctg02_33\|4883\|Hy... - protein	134.0	[0..15]	[207..372]
gi\|50731151 - gi\|50731151\|ref\|XP_417190.1\| PREDICTED: similar to hypothetical protein [Gallus gallus]	131.0	[0..1]	[259..26]

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Predicted Domain #1

Region A:
Residues: [1-110]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTAARPTFD PARGGSGRGE KDLSALSKQY SSRDLPGHTK LKYRETGQGT SDENRNRDFR  60
   61 KELEEREREA RSGTGATSSS SGKALPSIVR KAIEANNAGG GSSAAKRSKP

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	13.161151
Match:	PF04889.3
Description:	No description for PF04889.3 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.295	N/A	N/A	c.49.1	Pyruvate kinase, C-terminal domain
View	Download	0.278	N/A	N/A	a.77.1	DEATH domain
View	Download	0.250	N/A	N/A	a.21.1	HMG-box
View	Download	0.226	N/A	N/A	a.77.1	DEATH domain
View	Download	0.212	N/A	N/A	b.40.2	Bacterial enterotoxins

Predicted Domain #2

Region A:
Residues: [111-259]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAGQQQAQQA AQQQAANMDA DEPLDNDSSD SDSDSDDDDA ALLAELQKIK QERLQETARR  60
   61 ESEKKQEDER IRMENILSGN PLMNYEPGTA ASAAGRASGL GGDLKIKRRW DDDVVFKNCA 120
  121 RSAPDKKTHF VNDALRSDFH KKFMDKYIK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.09691
Match:	1w9rA
Description:	Solution Structure of Choline Binding Protein A, Domain R2, the Major Adhesin of Streptococcus pneumoniae
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits