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View Structure Prediction Details

Protein: Ir8a-PA
Organism: Drosophila melanogaster
Length: 936 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ir8a-PA.

Description E-value Query
Range
Subject
Range
gi|56280 - gi|56280|emb|CAA77778.1| kainate receptor [Rattus norvegicus]
565.0 [0..1] [907..17]

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Predicted Domain #1
Region A:
Residues: [1-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELPLLVLLL ALRFAGSEVL KITFWIEPVQ RAEFDTDIAM VLKELDALRL DVKVDDTTLT  60
   61 LTRSEDGLDM QRFCEILSTV GASAVIDLTY SHWEEGYNLV RSLGIGYVRL ERIMRPFLDM 120
  121 FGDFMRQKRA NNVAMVFMNA RDAVEAMQQM LVGYPFRTLI MDASQTDPGQ HFLERIRSLR 180
  181 PAPTYIALFA RAAAMNGIFE KVQKADLFQR PLEWHFVFLD TRDRVFKYRR QAELCTRFTL 240
  241 NPRAICRSMP MPDLYCGSGF TMQRAMLLNV LRSLINAAQV SPGYPLAIYQ DCNATASSSE 300
  301 VSDPLEKDDY NWLDMVHWSN FLAYAPPLPH IQDQFQSPVP GLTFAVNISA GYYSSEHEAK 360
  361 TDLAAWSSVG EMRLLNETIS PARRFFRIGT AESIPWSYLR REEGTGELIR DRSGLPIWEG 420
  421 YCIDFIIRLS QKLNFEFEIV APEVGHMGEL NEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.522879
Match: 2e4uA
Description: No description for 2e4uA was found.

Predicted Domain #2
Region A:
Residues: [454-578]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEWDGVVGDL VRGETDFAIA ALKMYSEREE VIDFLPPYYE QTGISIAIRK PVRRTSLFKF  60
   61 MTVLRLEVWL SIVAALVGTA IMIWFMDKYS PYSSRNNRQA YPYACREFTL RESFWFALTS 120
  121 FTPQG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.522879
Match: 1xt8A
Description: Crystal Structure of Cysteine-Binding Protein from Campylobacter jejuni at 2.0 A Resolution
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [579-848]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGEAPKAISG RMLVAAYWLF VVLMLATFTA NLAAFLTVER MQTPVQSLEQ LARQSRINYT  60
   61 VVKDSDTHQY FVNMKFAEDT LYRMWKELAL NASKDFKKFR IWDYPIKEQY GHILLAINSS 120
  121 QPVADAKEGF ANVDAHENAD YAFIHDSAEI KYEITRNCNL TEVGEVFAEQ PYAVAVQQGS 180
  181 HLGDELSYAI LELQKDRFFE ELKAKYWNQS NLPNCPLSED QEGITLESLG GVFIATLFGL 240
  241 VLAMMTLGME VLYYKKKQNA LEITQVRPVN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.221849
Match: 1yaeA
Description: Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [849-936]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSSGSGGNSS TAPPTATSTT KQAWHIPVLE AEEKPAKVSP PPSFETATFR GKKLPARITL  60
   61 GDGKFKPRHG LYARRNLGAS DSHSGYME

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle