






| Protein: | Upf2-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1241 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Upf2-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
804.0 | [0..48] | [1240..286] |
|
Region A: Residues: [1-370] |
1 11 21 31 41 51
| | | | | |
1 MLANDSATTD SEVSTPPSSR KDLADGVAEG DNDNDIDTGD TDANADEDVD AAAAIALEAE 60
61 EREELQQFIS ELREKIESKR QLRLQNSTIE LPGEEYFAKL DSNLKKNTAF VKKLKLFTAT 120
121 QLDGLLREIS ALNLSKYISE ICAALVEAKL KMTDVPAVVT LASRLHCTYA DFDVHFLEAW 180
181 QKALNIKATE KIGNPSKLRV DLRLFAELVS SGVIQMKPGL AQLGVVLVHL IALDKDDHSN 240
241 FSIILSFCRH CGEEYAGLVP QKMQQLATKY GVEVPKSDFL TADKQLNLRT MLKGYFKALC 300
301 KHVLAEQAEL MNMTKNIRRT MECKGEISTE KREKCELMQA GFDKLLASAQ SLSELLGEPL 360
361 PELAKESEGC
|
| Detection Method: | |
| Confidence: | 20.0 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB):![]() |
|
|
Region A: Residues: [371-473] |
1 11 21 31 41 51
| | | | | |
1 NPGTVIDNML DSASFGVLDP WGDEETRAFY TDLPDLRQFL PNFSAPKVDL ETLEEPSELT 60
61 EEAIDANLDA EMDLDDPPST TSDTTPENPI EEQPTTPVAA AED
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [474-728] |
1 11 21 31 41 51
| | | | | |
1 LKPQKMGNAL MELGRQQQQQ SQLNQNPIQI QNQMRQQFDG FLVNLFNCVN KELIDSAAIE 60
61 FLLNFNTKHQ RKKLTRTIFS VQRTRLDILP YLSRFVAIVH MCNTDVATDL AELLRKEFKW 120
121 HIHKKNQLNI ETKLKIVRFI GELVKFGLFK KFDALGCLKM LLRDFQHHQI EMACAFVEVT 180
181 GVYLYNCRDA RLLMNVFLDQ MLRLKTATAM DSRHAAQIES VYYLVKPPES SKREPMVRPA 240
241 MHEYIRYLIF EELCK
|
| Detection Method: | |
| Confidence: | 24.045757 |
| Match: | 1hu3A |
| Description: | Eukaryotic initiation factor eIF4G |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| RNA binding | 1.23334705954471 | bayes_pls_golite062009 |
| binding | 1.13433258588739 | bayes_pls_golite062009 |
| protein binding | 0.321971103983539 | bayes_pls_golite062009 |
| nucleic acid binding | 0.222038432626885 | bayes_pls_golite062009 |
| catalytic activity | 0.0114279309788371 | bayes_pls_golite062009 |
|
Region A: Residues: [729-958] |
1 11 21 31 41 51
| | | | | |
1 QNVDRCIKML RRIDWQDPET NCYAIKCLSK AYLLRFQLIR CLADLVSGLS SYQPRAVTIV 60
61 IDNVFEDIRA GLEIHSPRMA QRRIAMAKYL GEMYNYKLVE STNILNTLYS IISLGVSNDQ 120
121 NVVSPLDPPD SLFRLKLACM LLDTCAPYFT SQATRKKLDY FLVFFQHYYW FKKSHPVFSK 180
181 TENTSDLFPI LMDHTYRDCL LNVRPKLKIY KSLEQAKAAI DHLQEKLYPQ
|
| Detection Method: | |
| Confidence: | 96.221849 |
| Match: | 1uw4B |
| Description: | The structural basis of the interaction between nonsense mediated decay factors UPF2 and UPF3 |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| RNA binding | 1.23334705954471 | bayes_pls_golite062009 |
| binding | 1.13433258588739 | bayes_pls_golite062009 |
| protein binding | 0.321971103983539 | bayes_pls_golite062009 |
| nucleic acid binding | 0.222038432626885 | bayes_pls_golite062009 |
| catalytic activity | 0.0114279309788371 | bayes_pls_golite062009 |
|
Region A: Residues: [959-1025] |
1 11 21 31 41 51
| | | | | |
1 LKTTNNAQDP SLGTISEISE IDEGGTDEDS GSSNDQRERQ VSGQEQDQSN DWTENEAEPP 60
61 LPPLPPP
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1026-1241] |
1 11 21 31 41 51
| | | | | |
1 EKSKEDLEFE QLYEKMTTDS YQERLKEPIK ATAKDIPVPM MARLQKKSYD QITGAQTIGP 60
61 GINNMSQISK SVPNQDGTPG SPGADSPDGN GKSGGGVGGS DVGAAGAAGA SGATSVPFVL 120
121 MVRGHKGGKQ QFKSFVAPSD SHLATNLKRQ EQMIREEKEK VKRLTLNITE RIEEEDYQES 180
181 LMPPQHRNFT QSYYQKPNKH KFKHQKGAPD ADLIFH
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.