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View Structure Prediction Details

Protein: Ilp7-PA
Organism: Drosophila melanogaster
Length: 159 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ilp7-PA.

Description E-value Query
Range
Subject
Range
gi|125982075, gi... - gi|54643336|gb|EAL32080.1| GA12198-PA [Drosophila pseudoobscura], gi|125982075|ref|XP_001355024.1| G...
255.0 [0..11] [159..1]

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Predicted Domain #1
Region A:
Residues: [1-159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRMIIQNSG SWTLCGAVLL FVLPLIPTPE ALQHTEEGLE MLFRERSQSD WENVWHQETH  60
   61 SRCRDKLVRQ LYWACEKDIY RLTRRNKKRT GNDEAWIKKT TTEPDGSTWL HVNYANMFLR 120
  121 SRRSDGNTPS ISNECCTKAG CTWEEYAEYC PSNKRRNHY

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.1
Match: 3lriA
Description: Insulin-like growth factor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor binding 4.59183117612989 bayes_pls_golite062009
insulin-like growth factor receptor binding 3.91392491671741 bayes_pls_golite062009
growth factor activity 3.82223614188869 bayes_pls_golite062009
insulin receptor binding 3.29339271267896 bayes_pls_golite062009
binding 1.97432615074248 bayes_pls_golite062009
growth factor binding 1.64794458051288 bayes_pls_golite062009
insulin-like growth factor binding 1.58320511785821 bayes_pls_golite062009
protein binding 1.49599385682338 bayes_pls_golite062009
hormone activity 1.12793487496998 bayes_pls_golite062009
protein complex binding 1.04333094834193 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle