| Protein: | FBpp0300616, ple... |
| Organism: | Drosophila melanogaster |
| Length: | 2051 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0300616, ple....
| Description | E-value | Query Range |
Subject Range |
|
|
1768.0 | [0..1] | [2051..1] |
|
Region A: Residues: [1-774] |
1 11 21 31 41 51
| | | | | |
1 MLRKELYCAN IIHVLHVLCI IIILGSQHYC VNCIEELPAQ ALSPLNDIVA QFNLPSIPVQ 60
61 STASSYGNRS IGNNIESVRD SQSKNYFTHM SFDFMHNVLF AGATNKILKL NENLRVLAEA 120
121 VTGPLHDSPQ CHAGGCPEDI ETSLVNNFNK ILVVSYAHDG ILIACGSIRQ GACEIYSLPR 180
181 FPATPQFFAV PLAANDENAS TYAFVGPARY AWKEEDILYV GTTFTNVGDY RHDVPAISSR 240
241 RLDDLNYAEF SIQQSIINID VKYRDHFLVD YIYGFNSSEY AYFIIVQKKS HLADEAGYVT 300
301 RLARICITDP NYDSYTEITV QCTATENNVD YNIVRDAKVT PASHKLAQKM GIKKDDHVLV 360
361 TVFSPSREIS NQPESKSAMC IYSIKDIEDM FIENIHLCFN GTTKDRNLGY ISGTINDGRC 420
421 PIVGSLGNIY NFCSVGLKIS GVSPITAHAL FHFDNVSVTS VTATSTTDQQ HSLAFLGTNM 480
481 GVIKKVLLSG QSPGEYEEIV VDAGNRILPN TMMSPKKDFL YVLSQRKITK LRIEHCSVYT 540
541 NCSACLESRD PFCGWCSLEK RCTVRSTCQR DTSASRWLSL GSGQQCIEFE SIIPEKIPIS 600
601 ELSHLHLIIR TLPEPFNAKY RCVFGNSTPI DAEILENGLG CATPPLDERP LIPTNTDHIL 660
661 VPLSVRSSET NKDFVSRNFA FFDCSHHGNC QECLQSSWGC NWCIFDNKCV HKSLQCRNIE 720
721 NAVSTVGHCP HLKKNRPEIL LPVRVPIEIR LEIENLPKPK SAHAGFLCTI HIEA
|
| Detection Method: |  |
| Confidence: | 86.39794 |
| Match: | 2uzxB |
| Description: | No description for 2uzxB was found. |
|
Region A: Residues: [775-1110] |
1 11 21 31 41 51
| | | | | |
1 AQMLLPAHVE SNKIVVCEKT PYFYEINTHE YQAKVVVTWN FQHYVDTAIV TLYKCDVLGS 60
61 HREHPDCSLC VTRDPKYKCA WCSNSCVYNE TCIADKNSIS SGSKSAIENE CPLPRIDIIK 120
121 PLSGPVEGGT LITIEGSNLG IREEDVRGKI FIGSVPCELE NYQISVKIEC RTGASLYEMS 180
181 APIKVANDAG FTESSVQFHF KNVLLTGLYP TIGPRSGGTQ LSLIGKFLNI GSTMRAFLDE 240
241 YECHIDVTQA SSSQVSCTTS EATQPEPIRS LHLVIDGANR TLECQISTPS ITNTNPTRSN 300
301 FGSYQLRSLP RQPCSIFNYT QDPRIMQIKP LRSFKS
|
| Detection Method: | |
| Confidence: | 14.69897 |
| Match: | 1n7dA |
| Description: | Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ErbB-2 class receptor binding | 3.57510498491825 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 3.28829361940308 | bayes_pls_golite062009 |
| protein binding | 2.30744405151563 | bayes_pls_golite062009 |
| receptor binding | 1.70177010329948 | bayes_pls_golite062009 |
| binding | 1.63967303762968 | bayes_pls_golite062009 |
| growth factor activity | 0.59278308192712 | bayes_pls_golite062009 |
|
Region A: Residues: [1111-1374] |
1 11 21 31 41 51
| | | | | |
1 GGRVLTVHGI YLNSIQKPEL EVFYDNERVN KTSCVVINSN QMECPSPPVN YKFETFKKTN 60
61 RKMDTELHLQ NSSFQTETRY KNEYDRKKRR ADFGDTFRLY TNAGSSANYF VNNNMDVTTF 120
121 VKVHETQLNL QLSFVMDNVQ LVRNLNKYFH DIRSTIVYLA DPKYLPFPND GVKLYKGDSL 180
181 VIEGELLNLA ADEYDVNVTI GTSQCNITSL ALNQLLCIPP EQQPLPTDEN GVDQSTDLPL 240
241 VVVKVGRNLR FVIGYLKYDL NKPY
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1375-1629] |
1 11 21 31 41 51
| | | | | |
1 VFSHALLVGI LTVALLVVVF VIVLIIFRRK STQAEREYKR IQIQMITLES NVRSECKQAF 60
61 AELQTDMTDL TADLESTGIP TLDHVNYIMK VFFPGVSDHP ILNSPKFREG SPQTNYDAAM 120
121 VQFEQLIGNK YFLLMFIETL EAQRSSFSIR DRVNVASLIM VVLMNKMEYA TEILKSLLLR 180
181 LIDKSLASKH PQLMLRRTES VVEKMLTNYL AICMYDYLKE YAGSNLFLLF KAIKHQIEKG 240
241 LVDAITNDAR YSLSE
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1630-1742] |
1 11 21 31 41 51
| | | | | |
1 ERLLHEQVTH SVVILHILQD DLDEKVQCRV NDWDTISQVK LKILDAIFKN TPFSMRPSVN 60
61 EVDLEWRHGR GGHLTLQDED LTTKTVNGWK RLNTLAHYGV KESAVMSLIA RQN
|
| Detection Method: | |
| Confidence: | 38.522879 |
| Match: | 2r2oA |
| Description: | No description for 2r2oA was found. |
|
Region A: Residues: [1743-1837] |
1 11 21 31 41 51
| | | | | |
1 DNYHIPYSKN QNSAPYHNFY FINNSQSHII INNDIESGLQ QPRVYHLVKP NIPDHYMNIK 60
61 NSVLSGGSPA FQSHVVNNCN DRVNKTIPEV YLTRL
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1838-2051] |
1 11 21 31 41 51
| | | | | |
1 LATKGTIQKF VDDFFSIILT VNEELPPAVK WLFDLLDEAA RRHDIADTDI VHAWKSNCLP 60
61 LRFWVNFIKN PDFIFDVNKT YSVDSCLSVI AQTFMDACST SEHRLGKDSP SNKLLFAKDI 120
121 PNYRIMVKEF YRDVSRLPQI SDQEMSTAMQ QLSVRQNEEF DTISALKELY IYITKYKDQI 180
181 MESLETDINC RKMHLSRKLG NVAATLDGDC TSNC
|
| Detection Method: | |
| Confidence: | 1.83 |
| Match: | 1werA |
| Description: | RAS-GTPASE-ACTIVATING DOMAIN OF HUMAN P120GAP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| GTPase regulator activity | 3.95419914962876 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 3.92344045766502 | bayes_pls_golite062009 |
| small GTPase regulator activity | 3.59355391509857 | bayes_pls_golite062009 |
| GTPase activator activity | 3.54666073519034 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 3.44103045903863 | bayes_pls_golite062009 |
| enzyme regulator activity | 3.38464552177847 | bayes_pls_golite062009 |
| Rho GTPase activator activity | 3.20097433590483 | bayes_pls_golite062009 |
| Rac GTPase activator activity | 3.09114040497488 | bayes_pls_golite062009 |
| enzyme activator activity | 3.08850936101798 | bayes_pls_golite062009 |
| protein binding | 1.47356170396493 | bayes_pls_golite062009 |
| binding | 0.90203495506529 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 0.283174381383763 | bayes_pls_golite062009 |
