YRC Public Data Repository - Protein Structure Prediction

Protein:	CG18672-PA
Organism:	Drosophila melanogaster
Length:	235 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG18672-PA.

Description	E-value	Query Range	Subject Range
gi\|56554783 - gi\|56554783\|gb\|AAV97962.1\| carbonic anhydrase [Pseudopleuronectes americanus]	300.0	[0..1]	[233..1]
CAHZ_DANRE - Carbonic anhydrase OS=Danio rerio GN=cahz PE=1 SV=2	298.0	[0..3]	[233..5]
gi\|37221537 - gi\|37221537\|gb\|AAQ89896.1\| carbonic anhydrase [Oreochromis mossambicus]	296.0	[0..1]	[233..1]
CAH2_TRIHK - Carbonic anhydrase 2 OS=Tribolodon hakonensis GN=ca2 PE=2 SV=3	296.0	[0..3]	[233..5]
gi\|218931238, gi... - gi\|61506858\|dbj\|BAD36835.2\| carbonic anhydrase 1 [Oncorhynchus mykiss], dbj\|BAD36836.1\| carbonic anh...	292.0	[0..3]	[233..5]
gi\|22252956 - gi\|22252956\|gb\|AAM94169.1\| erythrocyte carbonic anhydrase [Lepisosteus osseus]	292.0	[0..3]	[233..5]
CAH2_RABIT - (P00919) Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonic anhydrase II) (Carbonate dehydratase II) (CA-II...	291.0	[0..2]	[232..3]
gi\|157834073, gi... - gi\|2098445\|pdb\|1UGF\| Chain , Human Carbonic Anhydrase Ii [hcaii] (E.C.4.2.1.1) Mutant With Ala 65 ...	291.0	[0..2]	[233..2]
gi\|109086851 - gi\|109086851\|ref\|XP_001096360.1\| PREDICTED: carbonic anhydrase II [Macaca mulatta]	290.0	[0..2]	[233..4]

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Predicted Domain #1

Region A:
Residues: [1-235]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEWNYLKNGK DWEDLCSSGK HQSPILLDSR TVSISLDIPV TSNGRKPFIT GGRLKGRYYA  60
   61 DGLHFHWGSY KSRGSEHLIN KRRFDAEIHI VHRNEKYRNI AQAVRQKDGL AVVAIMVAIV 120
  121 RKDNAKSTPL SRLMEAVVRV PIEDSNATVF GQSSLDQLIG GVSHRDFFTY EGSLTTPLCD 180
  181 ETVTWIVFTE TTTVTMSSVS KFWLLRDHWG HRLINNYRIV QDLNNRTVFY KKRMS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	79.0
Match:	1ugfA
Description:	HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY THR (A65T)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.59667704693142	bayes_pls_golite062009
protein binding	0.253736495664202	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: