YRC Public Data Repository - Protein Structure Prediction

Protein:	Npc2h-PA, FBpp02...
Organism:	Drosophila melanogaster
Length:	157 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Npc2h-PA, FBpp02....

Description	E-value	Query Range	Subject Range
gi\|25012683 - gi\|25012683\|gb\|AAN71436.1\| RE56164p [Drosophila melanogaster]	180.0	[0..1]	[157..10]
NPC2_BOVIN - Epididymal secretory protein E1 OS=Bos taurus GN=NPC2 PE=1 SV=1	171.0	[0..4]	[155..1]
gi\|74212648 - gi\|74212648\|dbj\|BAE31061.1\| unnamed protein product [Mus musculus]	165.0	[0..4]	[156..1]
gi\|27465565, gi\|... - gi\|34786047\|gb\|AAH58132.1\| Niemann-Pick disease, type C2 [Rattus norvegicus], gi\|27465565\|ref\|NP_775...	161.0	[0..4]	[155..1]
gi\|62896507 - gi\|62896507\|dbj\|BAD96194.1\| Niemann-Pick disease, type C2 precursor variant [Homo sapiens]	159.0	[0..18]	[156..16]

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Predicted Domain #1

Region A:
Residues: [1-157]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLSSLLPV AFALVLSSVS AEIVNFQTCE DSVDSCSISQ VRVTPCPEAN ANAACHIRRR  60
   61 HRFTMSFDFT PHFDADTLVA SLGWAKSENV ELPLLTMDQE ACKYTTCPVR SGVTQTYTNN 120
  121 MPADARFPLS PYTIRWALKD PVSQKRCCFT IDIKVVR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.69897
Match:	1nepA
Description:	Epididymal secretory protein E1 (Niemann-Pick C2 protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.879052093832773	bayes_pls_golite062009
protein binding	0.80731472263402	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: