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View Structure Prediction Details

Protein: CG6296-PA
Organism: Drosophila melanogaster
Length: 676 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG6296-PA.

Description E-value Query
Range
Subject
Range
LIPP_MOUSE - Pancreatic triacylglycerol lipase OS=Mus musculus GN=Pnlip PE=1 SV=1
424.0 [0..2] [392..1]

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Predicted Domain #1
Region A:
Residues: [1-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLCLLVLGC VIAASAWPVD QLSVRDHGIN GWFVPQREGG LRWIGKAEAE RQLEYYEAQE  60
   61 ALEGRLSTNT VNFYLYTLQN PSTGQQIKAT QDSIDGSFFN PQNPTRITIH GWNSNYKDGV 120
  121 NTRVADAWFQ YGDYNMIAVD WLRGRSLEYA SSVAGAPGAG KKVAALVDFL VEGYGMSLDT 180
  181 LEIVGFSLGA HVAGHTAKQV NSGKVGKVVG LDPASPLISY SNTEKRLSSD DALYVESIQT 240
  241 NGAILGFGQP IGKASFYMNG GRSQPGCGID ITGSCSHTKA VLYYVEALLW NNFPSIKCES 300
  301 SVDANKNNCG NTYSSVFMGA SINFFVAEGI FYVPVNKESP YGLGELNSGG EATTGTPEIT 360
  361 STTVDGEDES TTEVSTSTTT DKPEESTTEE PE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 116.0
Match: 1lpaB
Description: Pancreatic lipase, C-terminal domain; Pancreatic lipase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.866238607554457 bayes_pls_golite062009
hydrolase activity 0.52702612560045 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [393-555]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDSTTNGKPE ESSTTTEQPE DSTTTTEEPI DSTTEAPEDE STTSSPTDGG EQSTTEEPET  60
   61 TTEKPEETST SPIDTEDSTT KEPEDVSTTP KESEESTTSS PEDDDTTSAP GEDDDTTAAP 120
  121 GGDEEETTTE DPEETTTSPS DADDSTTEEP EEDTTTTKKP VEP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.17
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #3
Region A:
Residues: [556-676]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STTTEEPEDS TTEVPEESTT EEPDKETSTT NAEPEVTTTV EPDVDSTVDP EGDQSTREDL  60
   61 EDVSTTAVPT KLPSTTGVPP EVPITTLAPE VPSTSPPQDG NTKNIFIFNV FLVNVKIENK 120
  121 S

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle