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View Structure Prediction Details

Protein: CG42235-PC
Organism: Drosophila melanogaster
Length: 689 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG42235-PC.

Description E-value Query
Range
Subject
Range
gi|91084087 - gi|91084087|ref|XP_968449.1| PREDICTED: similar to sodium/solute symporter [Tribolium castaneum]
340.0 [0..99] [675..6]

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Predicted Domain #1
Region A:
Residues: [1-162]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTTADPVAL GVNSPVEDVV AKTTTTVANA IAKTVAVISS TVSTSSTTGA TSTISTSSST  60
   61 PTTSTTFAYT PTPTPTQSAS PSLEDGEEKL SVKDLSQALQ HFGIVDYLVF IAMLAVCAVI 120
  121 GFYFGFIEKK QKKQKLAGKD GGGAAGVEER RGSEALDYLV GG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.0
Match: 1mv3A
Description: NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [163-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RQMKVFPVAL SLVASFVSGI SLLGTSTEIY VYGTQYAFIL VTLAISGAIS WYIFLPVFCN  60
   61 LQLTSTYEYF QLRYGAGIRN LGSVLFIVGT MLWLPVALYV PAITYNQVTG TGIHVITPIV 120
  121 CTICTFYTCV GGLKAVVWTD VIQSFVMFGS ILAVCVKGTF DVGGLGVVLQ RNEDGGRLNA 180
  181 PELTWDPTVR LSMLSVILGG TLHKIQSSDV NQVSIQRFLS LPSYEHAKRC MLVFTVLLIF 240
  241 LLSCCSYMGL VSYAVYHDCD PISTKLAAAV DQLPSLLMMR TLGSLPGLPG LFVSGVFSAA 300
  301 LSSLSTGLNS LACVITQDIV RPLLKVPMTE RQTAFWLRAI VVVCGFCCLG MVNVVEKLGQ 360
  361 VVPLATSTAA VSMGPLLGIY CMGVGLPWVK GKSVLLGSVV SFLVLSWICI KAQLAQMHGE 420
  421 IRYPKLPVSV DGCDYDFDNQ TVHETIHEY

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.951
Match: 2a65A
Description: Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [612-689]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPSERNIYHL SFLWYTALGG FICTVVSVLA GFVFGWEDLN KMDPALITPC MRRFLPNKNY  60
   61 EAVKMQDLFK RKDEIESQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle