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View Structure Prediction Details

Protein: hh-PB
Organism: Drosophila melanogaster
Length: 471 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hh-PB.

Description E-value Query
Range
Subject
Range
gi|384220 - gi|384220|prf||1905316A hedgehog gene
590.0 [0..1] [471..1]

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Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNHSSVPWA SAASVTCLSL DAKCHSSSSS SSSKSAASSI SAIPQEETQT MRHIAHTQRC  60
   61 LSRLTSLVAL LLIVLPMVFS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [81-255]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAHSCGPGRG LGRHRARNLY PLVLKQTIPN LSEYTNSASG PLEGVIRRDS PKFKDLVPNY  60
   61 NRDILFRDEE GTGADRLMSK RCKEKLNVLA YSVMNEWPGI RLLVTESWDE DYHHGQESLH 120
  121 YEGRAVTIAT SDRDQSKYGM LARLAVEAGF DWVSYVSRRH IYCSVKSDSS ISSHV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.39794
Match: 2ibgE
Description: No description for 2ibgE was found.

Predicted Domain #3
Region A:
Residues: [256-471]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HGCFTPESTA LLESGVRKPL GELSIGDRVL SMTANGQAVY SEVILFMDRN LEQMQNFVQL  60
   61 HTDGGAVLTV TPAHLVSVWQ PESQKLTFVF ADRIEEKNQV LVRDVETGEL RPQRVVKVGS 120
  121 VRSKGVVAPL TREGTIVVNS VAASCYAVIN SQSLAHWGLA PMRLLSTLEA WLPAKEQLHS 180
  181 SPKVVSSAQQ QNGIHWYANA LYKVKDYVLP QSWRHD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.522879
Match: 1at0A
Description: 17-KDA FRAGMENT OF HEDGEHOG C-TERMINAL AUTOPROCESSING DOMAIN
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle