YRC Public Data Repository - Protein Structure Prediction

Protein:	CG4390-PA
Organism:	Drosophila melanogaster
Length:	286 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG4390-PA.

Description	E-value	Query Range	Subject Range
gi\|114649560 - gi\|114649560\|ref\|XP_001150093.1\| PREDICTED: esterase D/formylglutathione hydrolase isoform 2 [Pan tr...	241.0	[0..1]	[284..35]
ESTD_RAT - S-formylglutathione hydrolase OS=Rattus norvegicus GN=Esd PE=2 SV=1	241.0	[0..1]	[284..1]
gi\|73989006, gi\|... - gi\|73989008\|ref\|XP_855986.1\| PREDICTED: similar to esterase D/formylglutathione hydrolase isoform 2 ...	239.0	[0..1]	[284..1]
ESD - esterase D	239.0	[0..1]	[284..1]
gi\|61372767, gi\|... - gi\|61372772\|gb\|AAX43909.1\| esterase D/formylglutathione hydrolase [synthetic construct], gi\|61372767...	239.0	[0..1]	[284..1]
gi\|82952967 - gi\|82952967\|ref\|XP_894321.1\| PREDICTED: similar to esterase D/formylglutathione hydrolase [Mus muscu...	238.0	[0..1]	[284..1]
ESTD_PIG - S-formylglutathione hydrolase OS=Sus scrofa GN=ESD PE=2 SV=1	237.0	[0..1]	[284..1]

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Predicted Domain #1

Region A:
Residues: [1-286]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLEQLSANK CFEGEQRVYR HRSDTLKCDM TFGVFLPPAA LEGKPCPVLF FLSGLTCTHE  60
   61 NFIQKSGFQQ HAARHNLIVV NPDTSPRGVE IAGQDDAYDF GSGAGFYVDA KEEPWSKHYK 120
  121 MYSYVTQELV DVVNANLPVV PGKRGIFGHS MGGHGALICA LKNPGLYQSV SAFAPIANPT 180
  181 ECPWGKKAFA GYLGSNPDDW ALWDATHLVS QYESTPQELF IDQGAADNFL AGKQLLPENL 240
  241 LAAADGNDHI QTIFKQREGY DHSYFYIATF VAEHIAYHAA LLTASA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.30103
Match:	1pv1A
Description:	Crystal Structure Analysis of Yeast Hypothetical Protein: YJG8_YEAST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
S-formylglutathione hydrolase activity	2.11404818814754	bayes_pls_golite062009
hydrolase activity	1.75934962198703	bayes_pls_golite062009
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.09488027320166	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: