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View Structure Prediction Details

Protein: Fsh-PB, Fsh-PA
Organism: Drosophila melanogaster
Length: 831 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Fsh-PB, Fsh-PA.

Description E-value Query
Range
Subject
Range
gi|1518487, gi|1... - gi|1518487|gb|AAB07999.1| TSH, FSH, LH/CG receptor [Drosophila melanogaster], gi|1518464|gb|AAB07030...
396.0 [0..1] [831..1]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKHPSLSQR MGTTYRPRKG LKCLSFEFQC RLLLHHLLLT SLSGRHFVYA TSAVGGALSA  60
   61 NNCHDIHHGF DVYPNLTAVS LAQSTDTP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 1yrgA
Description: Rna1p (RanGAP1), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [89-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTATMPRSAW KCCCWNASNQ AEEVECRCEG DGLNRVPQTL TLPIQRLTIA SAGLPRLRHT  60
   61 GLKVYGSTLL DVAFTDCLQL ELIQDGAFAN LTLLRTIYIT NAPKLTFLSK DVFLGISDTV 120
  121 DIIRIINSGL TRVPDLGHLP PHNILQMIDL DNNQITRIDS KSIKVKTAQL ILTNNEISYV 180
  181 DDSAFFGSKI AKLSLKENKK LQMMHPNAFD GIIDITELDL SSTSLVGLPS AGLQNIEALY 240
  241 IQNTHTLKTI PSIYNFRNLQ RAYLTHSFHC CAFQFPSRHD PQRHAQRMLE IEKWRKQCKS 300
  301 DSGTRKERST LDNPFNMPED FGSF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.154902
Match: 1xwdC
Description: Crystal Structure of Human Follicle Stimulating Hormone Complexed with its Receptor
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [413-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGTDDSATDI TPITFASFDY MADDTMNKGT FHEKIILNPG DDSSAELCGN FT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [465-831]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FRKPNIECYP MPNDLNPCED VMGYQWLRIS VWIVVALAVV GNVAVLTVIL SIRPESTPVP  60
   61 RFLMCHLAFA DLCLGLYLLL VACIDAHSMG EYFNFAYDWQ YGLGCKVAGF LTVFASHLSV 120
  121 FTLTVITIER WLAITQAMYL NHRIKLRPAA LIMLGGWIYS MLMSSLPLFG ISNYSSTSIC 180
  181 LPMENRDVYD TIYLIAILGS NGVAFSIIAV CYAQIYLSLG RETRQAHQNS PGELSVAKKM 240
  241 ALLVFTNFAC WSPIAFFGLT ALAGYPLINV TKSKILLVFF YPLNSCADPY LYAILTSQYR 300
  301 QDLFTLLSKL GLCQQSALKY KDSLSGQATT RFTIHGSIQR HSSLTCKMQT VMGAETQKML 360
  361 KNSEDYV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.0
Match: 1f88A
Description: Rhodopsin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle