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View Structure Prediction Details

Protein: Cp190-PB, Cp190-PA
Organism: Drosophila melanogaster
Length: 1096 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Cp190-PB, Cp190-PA.

Description E-value Query
Range
Subject
Range
gi|76678552 - gi|76678552|ref|XP_583095.2| PREDICTED: similar to Zinc finger protein 268 (Zinc finger protein HZF3...
691.0 [0..88] [769..579]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEVKSVKVD NWGVFFLQKL QNFFNKTDYC DLTLQFRDNS QLKVHRLVLS ACTDYFNVLE  60
   61 QTCEIVDDAL IMPNEFQADV VVPIVNFMYT GTLEFELKMY GKLLRTAKEM NMTVLLKLLE 120
  121 AHRRTMENVN RQQRP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.69897
Match: 1r28A
Description: Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB domain to 2.2 Angstrom
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [136-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSPKGIRRRT VGQPSSGLPQ QRVLGPSPQS RNVATPIAQR ANTQRGSTGN TMSRTSGGSN  60
   61 RSPYGDSSNV KQEPTSPFEQ LRKGYNNNKR PAQTSLLSPP SKKPSLEEVK EFAEQQRMRK 120
  121 QIAAEYGDND PE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [268-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDGGMLYDDV HAGDDDDDDM PPQPSTSKQQ SPQGTQTQLE HGSTTIILKQ DSPSQTPTII  60
   61 VKDSSNAKLN HTKIIAEVLR QYPHIVKGHK NIKLKIMPNT PAAPTEKSAP ATVKPPANQS 120
  121 SATTSPHKKL HVSFKADKST PLITAQQKAA SSQQKSGTSQ TTGNQGTGAN PPANTAAAQK 180
  181 RRIDSKTMHA LIAQGAE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.69897
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #4
Region A:
Residues: [465-692]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTTGPWLCLR CGVNGRPISI PSYRGFRRHL INTHKETIDP ALCEHCGWRS VNNRELHFHM  60
   61 YMEHQTKSLL YTFAECALCN QSYRTKGELE AHINEVHTDD NKQQCIYCNK VFEQELQLYR 120
  121 HMKSYHKEQA LEDGIIDETD EEFLGSQDEE EEAEGDEEQE PEQTGKVRIL SDISLPATSA 180
  181 ITVQQAQQEQ LQEEDVEQVQ QEVKFVGADG NEVELTDEQR KEILSQLN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.69897
Match: 1tf6A
Description: Transcription factor IIIA, TFIIIA
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [693-756]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQQAGATAGG VVMVLSEPEA EHVKQETDEK SLAGTEEEYD DSQIYSELGA ADSVESAKKN  60
   61 IADE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [757-1096]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKESIDNLEW AENLIAESEE QSNKEPKSDK PRDDISEKLK ELTGDWTEDE NDDDVDDKPA  60
   61 TAELASELAN KDPEPTVHEE EDDIDLALQS LHKGPEEATE EKASEESVTS ADDAVDAVPN 120
  121 INSQPEKMDV DSEAADEKAS KAEVQIKKEA ELENDQEEFI KEDSPIPHSD SVAELREAVT 180
  181 ASEGEDDVHL EADNIRKELL DELIAEAEKP DQEKDIVQSE ENATTEALDR SVTDEDDLVP 240
  241 PTQVSTEQME IDEPAAEKAA ENNEDTRTAD EKEAVEDKPN QTQDVTTAEK PTLESAKAGD 300
  301 EATSGEAASV DKVKSLISEW GDDDEDEDEN GVSAAAKEEL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle